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Cancer, rapid ageing and nutrition – Martin Bergö's research group

Our group is interested in how free radicals and antioxidants interact with nutritional and metabolic needs of tumour cells during cancer development. Contrary to popular wisdom, antioxidants stimulate cancer metastasis and we are now exploring this finding to develop anti-metastatic drugs and to be able to give well-informed nutritional advice to cancer patients. We are also developing a new medicine for children with progeria – an accelerated ageing syndrome.

VÃ¥r forskning

Vi utvecklar också en ny strategi för behandling av barn med sjukdomen progeria (accelererat åldrande), då vi upptäckte att inhibering av ett enzym involverat i progeria effektivt kan minska symptom och öka livslängden hos möss med progeria.

Vi forskar i områdena basal biokemi, cellbiologi, molekylärbiologi, och genomik och använder oss av grundvetenskapliga, translationella, och kliniska angreppssätt.

För detaljerad information om vÃ¥r forskning, se gruppens engelska sida.

Publications

Selected publications

  • Article: CIRCULATION. 2019;140(1):67-79
    Bandaru S; Ala C; Salimi R; Akula MK; Ekstrand M; Devarakonda S; Karlsson J; Van den Eynden J; Bergstrom G; Larsson E; Levin M; Boren J; Bergo MO; Akyiirek LM
  • Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;228:742-748
    Dalin MG; Engström PG; Ivarsson EG; Unneberg P; Light S; Schaufelberger M; Gilljam T; Andersson B; Bergo MO
  • Article: NATURE IMMUNOLOGY. 2016;17(8):922-929
    Akula MK; Shi M; Jiang Z; Foster CE; Miao D; Li AS; Zhang X; Gavin RM; Forde SD; Germain G; Carpenter S; Rosadini CV; Gritsman K; Chae JJ; Hampton R; Silverman N; Gravallese EM; Kagan JC; Fitzgerald KA; Kastner DL; Golenbock DT; Bergo MO; Wang D
  • Article: ONCOGENE. 2016;35(10):1328-1333
    Cisowski J; Sayin VI; Liu M; Karlsson C; Bergo MO
  • Article: SCIENCE TRANSLATIONAL MEDICINE. 2015;7(308):308re8
    Le Gal K; Ibrahim MX; Wiel C; Sayin VI; Akula MK; Karlsson C; Dalin MG; Akyürek LM; Lindahl P; Nilsson J; Bergo MO
  • Article: LEUKEMIA. 2015;29(5):1032-1040
    Staffas A; Karlsson C; Persson M; Palmqvist L; Bergo MO
  • Article: SCIENCE TRANSLATIONAL MEDICINE. 2014;6(221):221ra15
    Sayin VI; Ibrahim MX; Larsson E; Nilsson JA; Lindahl P; Bergo MO
  • Article: SCIENCE. 2013;340(6138):1330-1333
    Ibrahim MX; Sayin VI; Akula MK; Liu M; Fong LG; Young SG; Bergo MO
  • Article: CIRCULATION. 2013;127(7):782-790
    Khan OM; Akula MK; Skålen K; Karlsson C; Ståhlman M; Young SG; Borén J; Bergo MO
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2011;121(2):628-639
    Khan OM; Ibrahim MX; Jonsson I-M; Karlsson C; Liu M; Sjogren A-KM; Olofsson FJ; Brisslert M; Andersson S; Ohlsson C; Hultén LM; Bokarewa M; Bergo MO
Keywords:
Cancer and Oncology Cell and Molecular Biology Medical Biotechnology (Focus on Cell Biology (incl. Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) Nutrition and Dietetics Vitamins
04-09-2025