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Disease mechanisms in severe acute bacterial infections – Anna Norrby-Teglund group

Our overall research goal is to decipher mechanisms contributing to severe manifestations of acute bacterial infections and thereby identify targets for therapeutic intervention. The research is translational in nature and is based largely on clinical isolates, patient materials and human cell and tissue model systems that mimic the clinical setting.

Part of the:
Group photo of ten people outdoors.

VÃ¥r forskning

Ett övergripande forskningsmål är att utröna mekanismer som bidrar till sjukdomsförloppet vid akuta bakteriella infektioner, såsom sepsis och svåra mjukdelsinfektioner, och därigenom identifiera mål för diagnostik och terapeutisk intervention.

Forskningen bygger till stor del på studier av kliniska bakterieisolat, patientmaterial och mänskliga cell- och vävnadsmodellsystem som efterliknar den kliniska miljön. Ett särskilt fokus ligger på individanpassad medicin, vilket har potential att erbjuda en mer precis och målinriktad diagnostik och behandling.

Läs mer om forskningen i Anna Norrby-Teglunds grupp på den engelska sidan.

Publications

Selected publications

  • Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2021;65(11):e0065821-10.1128/aac.00621
    Bergsten H; Medina LMP; Morgan M; Moll K; Skutlaberg DH; Skrede S; Wajima T; Svensson M; Norrby-Teglund A
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
    Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LMP; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgard J; Moll K; Garcia M; Maleki KT; Klingstrom J; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sonnerborg A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(14):149523
    Medina LMP; Rath E; Jahagirdar S; Bruun T; Madsen MB; Stralin K; Unge C; Hansen MB; Arnell P; Nekludov M; Hyldegaard O; Lourda M; Santos VAPMD; Saccenti E; Skrede S; Svensson M; Norrby-Teglund A
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
    Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
  • Article: CLINICAL INFECTIOUS DISEASES. 2021;72(2):293-300
    Bruun T; Rath E; Madsen MB; Oppegaard O; Nekludov M; Arnell P; Karlsson Y; Babbar A; Bergey F; Itzek A; Hyldegaard O; Norrby-Teglund A; Skrede S
  • Editorial comment: CLINICAL INFECTIOUS DISEASES. 2020;71(7):1772-1775
    Bergsten H; Madsen MB; Bergey F; Hyldegaard O; Skrede S; Arnell P; Oppegaard O; Itzek A; Perner A; Svensson M; Norrby-Teglund A
  • Editorial comment: CLINICAL INFECTIOUS DISEASES. 2020;70(7):1461-1462
    Norrby-Teglund A; Siemens N
  • Article: JOURNAL OF PROTEOME RESEARCH. 2020;19(2):688-698
    Afzal M; Saccenti E; Madsen MB; Hansen MB; Hyldegaard O; Skrede S; dos Santos VAPM; Norrby-Teglund A; Svensson M
  • Article: JOURNAL OF INNATE IMMUNITY. 2020;12(4):291-303
    Siemens N; Oehmcke-Hecht S; Hossmann J; Skorka SB; Nijhuis RHT; Ruppen C; Skrede S; Rohde M; Schultz D; Lalk M; Itzek A; Pieper DH; van den Bout CJ; Claas ECJ; Kuijper EJ; Mauritz R; Sendi P; Wunderink HF; Norrby-Teglund A
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(51):25923-25931
    Emgard J; Bergsten H; McCormick JK; Barrantes I; Skrede S; Sandberg JK; Norrby-Teglund A
  • Article: INTENSIVE CARE MEDICINE. 2019;45(9):1241-1251
    Madsen MB; Skrede S; Perner A; Arnell P; Nekludov M; Bruun T; Karlsson Y; Hansen MB; Polzik P; Hedetoft M; Rosen A; Saccenti E; Bergey F; dos Santos VAPM; Norrby-Teglund A; Hyldegaard O; Bidstrup D; Baernthsen NF; Frendo GH; Jansen EC; Madsen LB; Mueller RB; Pedersen EMJ; Petersen MW; Ravn F; Smidt-Nielsen IFG; Wahl AM; Wulffeld S; Aronsson S; Rosemar A; Trogen J; Nedrebo T; Oppegaard O; Rath E; Saevik M
  • Article: NATURE COMMUNICATIONS. 2019;10(1):3846
    Thaenert R; Itzek A; Hossmann J; Hamisch D; Madsen MB; Hyldegaard O; Skrede S; Bruun T; Norrby-Teglund A; Medina E; Pieper DH; Oppegaard O; Rath E; Nedrebo T; Arnell P; Rosen A; Polzik P; Hansen MB; Svensson M; Snall J; Karlsson Y; Nekludov M
  • Article: JOURNAL OF INFECTIOUS DISEASES. 2019;220(4):710-719
    Baude J; Bastien S; Gillet Y; Leblanc P; Itzek A; Tristan A; Bes M; Duguez S; Moreau K; Diep BA; Norrby-Teglund A; Henry T; Vandenesch F; Arnell P; Bergey F; Dos Santos VAPM; Hyldegaard O; Nekludov M; Pieper D; Skrede S; Svensson M
  • Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(6):1284-1293
    Keller N; Woytschak J; Heeb LEM; Maggio EM; Shambat SM; Snall J; Hyldegaard O; Boyman O; Norrby-Teglund A; Zinkernagel AS
  • Article: CLINICAL MICROBIOLOGY AND INFECTION. 2019;25(4):512.e7-512.e13
    Tarnutzer A; Andreoni F; Keller N; Zuercher C; Norrby-Teglund A; Schuepbach RA; Zinkernagel AS
  • Review: CLINICAL INFECTIOUS DISEASES. 2018;67(9):1434-1436
    Parks T; Wilson C; Curtis N; Norrby-Teglund A; Sriskandan S
  • Article: SCIENTIFIC REPORTS. 2018;8(1):13428
    Alpkvist H; Athlin S; Molling P; Norrby-Teglund A; Stralin K
  • Article: FRONTIERS IN IMMUNOLOGY. 2018;9:236
    Westman J; Chakrakodi B; Snall J; Morgelin M; Madsen MB; Hyldegaard O; Neumann A; Frick I-M; Norrby-Teglund A; Bjorck L; Herwald H
  • Article: JOURNAL OF INNATE IMMUNITY. 2018;10(1):30-43
    Neumann A; Papareddy P; Westman J; Hyldegaard O; Snall J; Norrby-Teglund A; Herwald H
  • Article: INTENSIVE CARE MEDICINE. 2017;43(11):1585-1593
    Madsen MB; Hjortrup PB; Hansen MB; Lange T; Norrby-Teglund A; Hyldegaard O; Perner A
  • Show more

Staff and contact

Group leader

All members of the group

Keywords:
Immunology in the Medical Area Infectious Medicine Microbiology in the Medical Area
Content reviewer:
Anna Norrby-Teglund
Karin Vikström
04-09-2025