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Yenan Bryceson group

We strive to identify molecular causes of hyperinflammatory disorders and understand the role of lymphocyte cytotoxicity in health and disease. We aim to develop new conceptualizations of immunological disorders, and combine basic immunological and genetic insights with potent immunotherapeutic interventions for the development of personalized treatment of disease. Our ultimate goal is to harness fundamental insights of the human immune system to develop cytotoxic cell therapies to fight cancer.

Part of the:

Publications

Selected publications

  • Article: SCIENCE IMMUNOLOGY. 2023;8(82):eabn0484
    Helm EY; Zelenka T; Cismasiu VB; Islam S; Silvane L; Zitti B; Holmes TD; Drashansky TT; Kwiatkowski AJ; Tao C; Dean J; Obermayer AN; Chen X; Keselowsky BG; Zhang W; Huo Z; Zhou L; Sheridan BS; Conejo-Garcia JR; Shaw TI; Bryceson YT; Avram D
  • Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(7):e20220202
    Campbell TM; Liu Z; Zhang Q; Moncada-Velez M; Covill LE; Zhang P; Darazam IA; Bastard P; Bizien L; Bucciol G; Enoksson SL; Jouanguy E; Karabela SN; Khan T; Kendir-Demirkol Y; Augusto Arias A; Mansouri D; Marits P; Marr N; Migeotte I; Moens L; Ozcelik T; Pellier I; Sendel A; Senoglu S; Shahrooei M; Smith CIE; Vandernoot I; Willekens K; Yasar KK; Bergman P; Abel L; Cobat A; Casanova J-L; Meyts I; Bryceson YT
  • Article: CELL STEM CELL. 2021;28(12):2062-2075.e5
    Woan KV; Kim H; Bjordahl R; Davis ZB; Gaidarova S; Goulding J; Hancock B; Mahmood S; Abujarour R; Wang H; Tuininga K; Zhang B; Wu C-Y; Kodal B; Khaw M; Bendzick L; Rogers P; Ge MQ; Bonello G; Meza M; Felices M; Huffman J; Dailey T; Lee TT; Walcheck B; Malmberg KJ; Blazar BR; Bryceson YT; Valamehr B; Miller JS; Cichocki F
  • Article: BLOOD. 2021;137(15):2033-2045
    Kalinichenko A; Casoni GP; Dupre L; Trotta L; Huemer J; Galgano D; German Y; Haladik B; Pazmandi J; Thian M; Petronczki OY; Chiang SC; Taskinen M; Hekkala A; Kauppila S; Lindgren O; Tapiainen T; Kraakman MJ; Vettenranta K; Lomakin AJ; Saarela J; Seppanen MRJ; Bryceson YT; Boztug K
  • Article: SCIENCE IMMUNOLOGY. 2021;6(57):eabc9801
    Holmes TD; Pandey RV; Helm EY; Schlums H; Han H; Campbell TM; Drashansky TT; Chiang S; Wu C-Y; Tao C; Shoukier M; Tolosa E; Von Hardenberg S; Sun M; Klemann C; Marsh RA; Lau CM; Lin Y; Sun JC; Mansson R; Cichocki F; Avram D; Bryceson YT
  • Article: SCIENCE IMMUNOLOGY. 2018;3(29):eaat9781
    Wu C; Espinoza DA; Koelle SJ; Yang D; Truitt L; Schlums H; Lafont BA; Davidson-Moncada JK; Lu R; Kaur A; Hammer Q; Li B; Panch S; Allan DA; Donahue RE; Childs RW; Romagnani C; Bryceson YT; Dunbar CE
  • Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2018;215(9):2379-2395
    Cichocki F; Wu C-Y; Zhang B; Felices M; Tesi B; Tuininga K; Dougherty P; Taras E; Hinderlie P; Blazar BR; Bryceson YT; Miller JS
  • Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;142(1):317-321.e8
    Tesi B; Rascon J; Chiang SCC; Burnyte B; L枚fstedt A; Fasth A; Heizmann M; Juozapaite S; Kiudeliene R; Kvedaraite E; Miseviciene V; Muleviciene A; M眉ller M-L; Nordenskj枚ld M; Matuzeviciene R; Samaitiene R; Speckmann C; Stankeviciene S; Zekas V; Voss M; Ehl S; Vaiciene-Magistris N; Henter J-I; Meeths M; Bryceson YT
  • Article: BLOOD. 2017;129(16):2266-2279
    Tesi B; Davidsson J; Voss M; Rahikkala E; Holmes TD; Chiang SCC; Komulainen-Ebrahim J; Gorcenco S; Nilsson AR; Ripperger T; Kokkonen H; Bryder D; Fioretos T; Henter J-I; Mottonen M; Niinimaki R; Nilsson L; Pronk CJ; Puschmann A; Qian H; Uusimaa J; Moilanen J; Tedgard U; Cammenga J; Bryceson YT
  • Article: BLOOD. 2017;129(14):1927-1939
    Schlums H; Jung M; Han H; Theorell J; Bigley V; Chiang SCC; Allan DSJ; Davidson-Moncada JK; Dickinson RE; Holmes TD; Hsu AP; Townsley D; Winkler T; Wang W; Aukrust P; Nordoy I; Calvo KR; Holland SM; Collin M; Dunbar CE; Bryceson YT
  • Article: IMMUNITY. 2017;46(2):287-300
    Cheuk S; Schlums H; Serezal IG; Martini E; Chiang SC; Marquardt N; Gibbs A; Detlofsson E; Introini A; Forkel M; Hoog C; Tjernlund A; Michaelsson J; Folkersen L; Mjosberg J; Blomqvist L; Ehrstrom M; Stahle M; Bryceson YT; Eidsmo L
  • Article: JOURNAL OF CELL BIOLOGY. 2015;210(1):135-151
    Marshall MR; Pattu V; Halimani M; Maier-Peuschel M; M眉ller M-L; Becherer U; Hong W; Hoth M; Tschernig T; Bryceson YT; Rettig J
  • Article: IMMUNITY. 2015;42(3):443-456
    Schlums H; Cichocki F; Tesi B; Theorell J; Beziat V; Holmes TD; Han H; Chiang SCC; Foley B; Mattsson K; Larsson S; Schaffer M; Malmberg K-J; Ljunggren H-G; Miller JS; Bryceson YT

Staff and contact

Group leader

All members of the group

Keywords:
Cell and Molecular Biology Cytotoxicity, Immunologic Hematology Immunology in the Medical Area Immunotherapy Show all
Content reviewer:
Yenan Bryceson
Karin Vikstr枚m
04-09-2025