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Anna Krook

Anna Krook

Professor
Telephone: +46852487824
Visiting address: Solnavägen 9, Biomedicum C4, 17165 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa Integrativ Fysiologi, 171 77 Stockholm
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About me

  • I am a Professor of Integrative Physiology at the Department of Physiology and Pharmacology and chair of the Strategic Research Programme in Diabetes at ̽»¨¾«Ñ¡. (Photo credit Yanan Li)

    Link to /en/srp-diabetes/strategic-research-programme-in-diabetes-srp-diabetes

    Education
    Bachelor of Science (Class I, Hons), Biological Sciences, University of East Anglia, United Kingdom;

    Master of Science, Department of Pathology, Queens University, Canada;

    Doctor of Philosophy, School of Clinical Medicine, University of Cambridge, United Kingdom

Research

  • I completed my doctoral studies at the University of Cambridge, UK, focusing on insulin receptor mutations in patients with severe syndromes of insulin resistance. Since then my research interest is focused on understanding insulin action at the molecular level. Work in my research group is currently focused on three broad areas, all centred around skeletal muscle metabolism. These include understanding the role non-coding RNA directs muscle metabolism and insulin sensitivity, transcriptional regulation of skeletal muscle metabolism and the effects of metabolites, hormones and other circulatory factors. We are interested in how insulin sensitivity and glucose metabolism are affected by type 2 diabetes and by exercise, both at the cellular level and by studying people with or without type 2 diabetes after various exercise interventions.

     

     

     

     

    Link to the research group home page is here: /en/fyfa/integrative-physiology

Teaching

  • I am course director for the 15 credit course in the Master's Programme in Translational Physiology and Pharmacology, given in the spring every year. Please find link below:

Articles

  • Article: CELL. 2025;188(15):4106-4122.e16
    Kjaergaard J; Stocks B; Henderson J; Freemantle JB; Rizo-Roca D; Puglia M; Montoya MM; Andersson D; Backdahl J; Eriksson-Hogling D; Stidsen JV; Wierer M; Rasmussen S; Sakamoto K; Hojlund K; Ryden M; Zierath JR; Krook A; Deshmukh AS
  • Article: MOLECULAR METABOLISM. 2025;92:102081
    Katayama M; Nomura K; Mudry JM; Chibalin AV; Krook A; Zierath JR
  • Article: SCIENCE TRANSLATIONAL MEDICINE. 2024;16(768):eado3022
    Rizo-Roca D; Guimaraes DSPSF; Pendergrast LA; Di Leo N; Chibalin AV; Maqdasy S; Ryden M; Naslund E; Zierath JR; Krook A
  • Article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2024;15(4):1335-1347
    Guimaraes DSPSF; Barrios NMF; de Oliveira AG; Rizo-Roca D; Jollet M; Smith JAB; Araujo TR; da Cruz MV; Marconato E; Hirabara SM; Vieira AS; Krook A; Zierath JR; Silveira LR
  • Article: MOLECULAR METABOLISM. 2024;86:101968
    Nomura K; Kinoshita S; Mizusaki N; Senga Y; Sasaki T; Kitamura T; Sakaue H; Emi A; Hosooka T; Matsuo M; Okamura H; Amo T; Wolf AM; Kamimura N; Ohta S; Itoh T; Hayashi Y; Kiyonari H; Krook A; Zierath JR; Kasuga M; Ogawa W
  • Article: NATURE METABOLISM. 2024;6(7):1329-1346
    Lecoutre S; Maqdasy S; Rizo-Roca D; Renzi G; Vlassakev I; Alaeddine LM; Higos R; Jalkanen J; Zhong J; Zareifi DS; Frendo-Cumbo S; Massier L; Hodek O; Juvany M; Moritz T; de Castro Barbosa T; Omar-Hmeadi M; Lopez-Yus M; Merabtene F; Abatan JB; Marcelin G; El Hachem E-J; Rouault C; Bergo MO; Petrus P; Zierath JR; Clement K; Krook A; Mejhert N; Ryden M
  • Article: NATURE METABOLISM. 2024;6(6):1024-1035
    Jiang S; Yuan T; Rosenberger FA; Mourier A; Dragano NRV; Kremer LS; Rubalcava-Gracia D; Hansen FM; Borg M; Mennuni M; Filograna R; Alsina D; Misic J; Koolmeister C; Papadea P; de Angelis MH; Ren L; Andersson O; Unger A; Bergbrede T; Di Lucrezia R; Wibom R; Zierath JR; Krook A; Giavalisco P; Mann M; Larsson N-G
  • Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2024;155:155834
    Pendergrast LA; Ashcroft SP; Ehrlich AM; Treebak JT; Krook A; Dollet L; Zierath JR
  • Article: CELL REPORTS MEDICINE. 2024;5(1):101348
    Dollet L; Lundell LS; Chibalin AV; Pendergrast LA; Pillon NJ; Lansbury EL; Elmastas M; Frendo-Cumbo S; Jalkanen J; Barbosa TDC; Cervone DT; Caidahl K; Dmytriyeva O; Deshmukh AS; Barres R; Ryden M; Wallberg-Henriksson H; Zierath JR; Krook A
  • Journal article: DIABETES. 2023;72(Supplement_1)
    GATTU A; KROOK A; ZIERATH JR; MANN M; RONALD KAHN C
  • Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2023;324(4):E289-E298
    Abdelmoez AM; Dmytriyeva O; Zurke Y-X; Trauelsen M; Marica AA; Savikj M; Smith JAB; Monaco C; Schwartz TW; Krook A; Pillon NJ
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(8):e2218510120
    Pendergrast LA; Lundell LS; Ehrlich AM; Ashcroft SP; Schoenke M; Basse AL; Krook A; Treebak JT; Dollet L; Zierath JR
  • Article: LIFE SCIENCE ALLIANCE. 2023;6(1):e202201598
    Pillon NJ; Puig LS; Altintas A; Kamble PG; Casani-Galdon S; Gabriel BM; Barres R; Conesa A; Chibalin AV; Naslund E; Krook A; Zierath JR
  • Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2022;135:155268
    Savikj M; Stocks B; Sato S; Caidahl K; Krook A; Deshmukh AS; Zierath JR; Wallberg-Henriksson H
  • Article: SCIENCE ADVANCES. 2022;8(36):eabo3192
    Pillon NJ; Smith JAB; Alm PS; Chibalin AV; Alhusen J; Arner E; Carninci P; Fritz T; Otten J; Olsson T; de ten Ryen SVD; Deldicque L; Caidahl K; Wallberg-Henriksson H; Krook A; Zierath JR
  • Article: NATURE GENETICS. 2022;54(9):1332-1344
    Wang Z; Emmerich A; Pillon NJ; Moore T; Hemerich D; Cornelis MC; Mazzaferro E; Broos S; Ahluwalia TS; Bartz TM; Bentley AR; Bielak LF; Chong M; Chu AY; Berry D; Dorajoo R; Dueker ND; Kasbohm E; Feenstra B; Feitosa MF; Gieger C; Graff M; Hall LM; Haller T; Hartwig FP; Hillis DA; Huikari V; Heard-Costa N; Holzapfel C; Jackson AU; Johansson A; Jorgensen AM; Kaakinen MA; Karlsson R; Kerr KF; Kim B; Koolhaas CM; Kutalik Z; Lagou V; Lind PA; Lorentzon M; Lyytikainen L-P; Mangino M; Metzendorf C; Monroe KR; Pacolet A; Perusse L; Pool R; Richmond RC; Rivera NV; Robiou-Du-Pont S; Schraut KE; Schulz C-A; Stringham HM; Tanaka T; Teumer A; Turman C; Van der Most PJ; Vanmunster M; Van Rooij FJA; Van Vliet-Ostaptchouk JV; Zhang X; Zhao J-H; Zhao W; Balkhiyarova Z; Balslev-Harder MN; Baumeister SE; Beilby J; Blangero J; Boomsma DI; Brage S; Braund PS; Brody JA; Bruinenberg M; Ekelund U; Liu C-T; Cole JW; Collins FS; Cupples LA; Esko T; Enroth S; Faul JD; Fernandez-Rhodes L; Fohner AE; Franco OH; Galesloot TE; Gordon SD; Grarup N; Hartman CA; Heiss G; Hui J; Illig T; Jago R; James A; Joshi PK; Jung T; Kahonen M; Kilpelainen TO; Koh W-P; Kolcic I; Kraft PP; Kuusisto J; Launer LJ; Li A; Linneberg A; Luan J; Vidal PM; Medland SE; Milaneschi Y; Moscati A; Musk B; Nelson CP; Nolte IM; Pedersen NL; Peters A; Peyser PA; Power C; Raitakari OT; Reedik M; Reiner AP; Ridker PM; Rudan I; Ryan K; Sarzynski MA; Scott LJ; Scott RA; Sidney S; Siggeirsdottir K; Smith AV; Smith JA; Sonestedt E; Strom M; Tai ES; Teo KK; Thorand B; Toenjes A; Tremblay A; Uitterlinden AG; Vangipurapu J; Van Schoor N; Volker U; Willemsen G; Williams K; Wong Q; Xu H; Young KL; Yuan JM; Zillikens MC; Zonderman AB; Ameur A; Bandinelli S; Bis JC; Boehnke M; Bouchard C; Chasman DI; Smith GD; De Geus EJC; Deldicque L; Dorr M; Evans MK; Ferrucci L; Fornage M; Fox C; Garland TJ; Gudnason V; Gyllensten U; Hansen T; Hayward C; Horta BL; Hypponen E; Jarvelin M-R; Johnson WC; Kardia SLR; Kiemeney LA; Laakso M; Langenberg C; Lehtimaki T; Le Marchand L; Magnusson PKE; Martin NG; Melbye M; Metspalu A; Meyre D; North KE; Ohlsson C; Oldehinkel AJ; Orho-Melander M; Pare G; Park T; Pedersen O; Penninx BWJH; Pers TH; Polasek O; Prokopenko I; Rotimi CN; Samani NJ; Sim X; Snieder H; Sorensen TIA; Spector TD; Timpson NJ; Van Dam RM; Van der Velde N; Van Duijn CM; Vollenweider P; Volzke H; Voortman T; Waeber G; Wareham NJ; Weir DR; Wichmann H-E; Wilson JF; Hevener AL; Krook A; Zierath JR; Thomis MAI; Loos RJF; Den Hoed M
  • Article: DIABETES. 2022;71(4):624-636
    Dollet L; Kuefner M; Caria E; Rizo-Roca D; Pendergrast L; Abdelmoez AM; Karlsson HKR; Bjornholm M; Dalbram E; Treebak JT; Harada J; Naslund E; Ryden M; Zierath JR; Pillon NJ; Krook A
  • Article: NATURE METABOLISM. 2022;4(2):190-202
    Maqdasy S; Lecoutre S; Renzi G; Frendo-Cumbo S; Rizo-Roca D; Moritz T; Juvany M; Hodek O; Gao H; Couchet M; Witting M; Kerr A; Bergo MO; Choudhury RP; Aouadi M; Zierath JR; Krook A; Mejhert N; Ryden M
  • Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2021;321(5):C770-C778
    Gonzalez-Franquesa A; Stocks B; Borg ML; Kuefner M; Dalbram E; Nielsen TS; Agrawal A; Pankratova S; Chibalin AV; Karlsson HKR; Gheibi S; Bjornholm M; Jorgensen NR; Clemmensen C; Hostrup M; Treebak JT; Krook A; Zierath JR; Deshmukh AS
  • Article: SCIENCE ADVANCES. 2021;7(43):eabi9654
    Gabriel BM; Smith JAB; Sardon-Puig L; Zhang X; Basse AL; Laker RC; Gao H; Liu Z; Dollet L; Treebak JT; Zorzano A; Huo Z; Ryden M; Lanner JT; Esser KA; Barres R; Pillon NJ; Krook A; Zierath JR
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Employments

  • Professor, Department of Physiology and Pharmacology, ̽»¨¾«Ñ¡, 2010-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2002

Distinction and awards

  • The DPLU/LUDC Nordic Prize, DPLU/LUDC, 2013

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