探花精选

Arun Selvam

Arun Selvam

Postdoctoral Researcher
Visiting address: Nobels v盲g 7, 17165 Solna
Postal address: H5 Laboratoriemedicin, H5 Patologi Bj枚rnstedt, 141 52 Huddinge

About me

  • Arun Selvam is a researcher at 探花精选 with a focus on translational oncology and redox-based cancer therapy. His work bridges enzymology, molecular biology, and systems-level analyses to understand how selenium compounds, particularly Se-methylselenocysteine (MSC), can be harnessed for targeted therapy in hepatopancreatobiliary and pancreatic cancers. He has contributed to key publications on KYAT1 enzyme modulation, selenium metabolism, and omics-driven cancer research, and is actively engaged in developing innovative therapeutic strategies through enzyme engineering, transcriptomics, and ex vivo patient tissue models.

Research

  • My research focuses on selenium-based redox therapy in cancer, particularly the metabolism of Se-methylselenocysteine (MSC) and the role of KYAT1 in therapeutic modulation. I am interested in integrating enzymology, transcriptomics, and ex vivo patient models to uncover tumor-specific vulnerabilities in hepatopancreatobiliary and pancreatic cancers. In addition, I explore innovative approaches such as lipid nanoparticle (LNP)  mediated mRNA delivery, affibody-based targeting, and cancer-specific microRNAs to develop new strategies for targeted therapy and personalized medicine.

Articles

  • Journal article: BIOCHEMICAL PHARMACOLOGY. 2025;239:117038
    Szekerczes T; Reszegi A; Selvam AK; Matyasi B; Pesti A; Sebestyen A; Lendvai G; Bjornstedt M; Kiss A
  • Article: TRANSLATIONAL ONCOLOGY. 2025;61:102512
    Nilvebrant J; Moro CF; Papalanis E; Novin MO; Ding H; Li R; Oroujeni M; Selvam A; Bozoky B; Graslund T; Szekerczes T; Sandalova T; Salter H; Achour A; Tolmachev V; Bjornstedt M; Nygren P-A
  • Journal article: BIOCHEMICAL JOURNAL. 2025;482(16):1163-1180
    Selvam AK; Sun R; Razaghi A; Salter H; Sandalova T; Bjornstedt M; Achour A
  • Article: ANTIOXIDANTS. 2023;12(1):167
    Szekerczes T; Selvam AK; Moro CF; Elduayen SP; Dillner J; Bjornstedt M; Ghaderi M
  • Article: FRONTIERS IN ONCOLOGY. 2022;12:965182
    Moro CF; Selvam AK; Ghaderi M; Pimenoff VN; Gerling M; Bozoky B; Elduayen SP; Dillner J; Bjoernstedt M
  • Article: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2022;662:25-62
    Selvam AK; Szekercz茅s T; Bj枚rnstedt S; Razaghi A; Bj枚rnstedt M
  • Article: ANTIOXIDANTS. 2021;10(7):1094
    Selvam AK; Jawad R; Gramignoli R; Achour A; Salter H; Bjornstedt M
  • Article: PATHOLOGY & ONCOLOGY RESEARCH. 2020;26(4):2669-2681
    Lendvai G; Szekerczes T; Kontsek E; Selvam A; Szakos A; Schaff Z; Bjornstedt M; Kiss A
  • Article: ANTIOXIDANTS. 2020;9(2):E139-139
    Selvam AK; Bjornstedt M
  • Article: ONCOTARGET. 2016;7(46):74686-74700
    Misra S; Selvam AK; Wallenberg M; Ambati A; Matolcsy A; Magalhaes I; Lauter G; Bjornstedt M
  • Article: INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY. 2014;304(3-4):351-359
    Pramanik A; K枚nninger U; Selvam A; Braun V

All other publications

  • Preprint: MDPI AG. 2025
    Selvam AK; Ghaderi M; Dillner J; Majeed S; Bj枚rnstedt M
  • Preprint: BIORXIV. 2025
    Selvam AK; Sun R; Razaghi A; Salter H; Sandalova T; Bj枚rnstedt M; Achour A
  • Preprint: ELSEVIER BV. 2025
    Selvam A; Ghaderi M; Bj枚rnstedt M; Dillner J
  • Preprint: ELSEVIER BV. 2025
    Nygren P-脜; Papalanis E; Novin M; Ding H; Li R; Nilvebrant J; Moro C; Tolmachev V; Oroujeni M; Selvam A; Boz贸ky B; Gr盲slund T; Szekerczes T; Sandalova T; Salter H; Achour A; Bj枚rnstedt M
  • Doctoral thesis: 2021
    Selvam AK
  • Preprint: BIORXIV. 2021
    Selvam AK; Jawad R; Gramignoli R; Achour A; Salter H; Bj枚rnstedt M
  • Book chapter: SELENIUM: MOLECULAR AND INTEGRATIVE TOXICOLOGY. 2018;p. 251-269
    Selvam AK; Bj枚rnstedt M; Misra S
  • Review: NUTRIENTS. 2015;7(5):3536-3556
    Misra S; Boylan M; Selvam A; Spallholz JE; Bjornstedt M

Employments

  • Postdoctoral Researcher, Department of Laboratory Medicine, 探花精选, 2021-2025

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, 探花精选, 2021

News from KI

Events from KI