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Homira Behbahani

Homira Behbahani

Affiliated to Research | Docent
Visiting address: Blickagången 16, 14152 Huddinge
Postal address: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Klinisk geriatrik Darreh-Shori, 171 77 Stockholm
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About me

  • I am supervisor for a research group, which right now consists of one PhD
    student, and three master students. My research is focused on understanding
    the molecular mechanism behind Alzheimer Disease with focused on Omi/HtrA2
    protease and amyloid beta uptake, and focus on vascular smooth muscle cell
    degeneration and proliferation in CADASIL as well as small vessel diseases.
    In addition to supervising, I am as a researcher involved in teaching at both
    the masters, advanced and doctoral level. Furthermore, I am organizer for
    “PhD/PostDoc” and “Center for Alzheimer Research” seminar series at
    NVS. This role gives me a lot of input and reflections to my own leadership
    style and also I learn to know PhD students at KI, which is a benefit for my
    research career.
    I am representative for “Equal treatment” (Ombud for Lika Villkor) at NVS
    since 2011. Therefore, I am a member of department council and work
    environment council at NVS. This role also gives me the opportunity to be
    involved in many issues related to employees and PhD/PostDoc student’s
    welfare and activities.
    Virology price 2002 Recipient of scholarship and Chosen by Sven Gard
    Stiftelse for the best thesis in Virology area.
    Scholarships 2001 and 2006: Recipient of scholarships of Keystone Symposia
    and being invited speaker.
    2008 Recipient of one year postdoctoral fellowship from Loo and Hans
    Ostermans stiftelse.
    1987 Bsc in Graphic Design, Tehran University Tehran, Iran.
    1997 BSc in Biomedicine, ̽ѡ, Stockholm, Sweden.
    2002 Ph.D in Experimental Medicine at Inst. of Medicine, Div. of Centre for
    infectious Medicine (CIM), at ̽ѡ, Stockholm, Sweden.
    Thesis title: Immune Dysregulation in HIV-1 Infected Lymphoid Tissue,
    Supervisors: Professor Anna-Lena Spetz (PhD, MD) and Professor Jan Andersson
    (MD, PhD)
    2011, April 26, Associates Professor in Neurobiology, NVS, KI
    2013 Project Leadership for Research Group Leader (PFL), invited by NVS
    institution
    2014 Leadership, higher Education for supervisor course at LIME, KI

Research

  • My research is focused on studying the degeneration and proliferation of
    vascular smooth muscle cells in CADASIL as well as small vessel diseases or
    stroke. We are also studying the toxicity of extracellular NOTCH3 and the
    role of autophagy or lysososmal function on intracellular aggregated NOTCH3.
    In my group we look specifically for finding biomarkers for CADASIL and will
    compared it to Alzheimer disease, stroke and vascular dementia diseases. Our
    aim is to provide a better understanding of the pathogenesis of CADASIL which
    would improve the prognosis of CADASIL and patients with other cerebral small
    vessel diseases.
    Furthermore, I am investigating the role of Omi/HtrA2 protease, a
    multifunctional serine protease, in Alzheimer disease and the mechanisms
    behind amyloid beta uptake in human primary neurons.

Articles

  • Article: ALZHEIMERS RESEARCH & THERAPY. 2023;15(1):137
    Tambaro S; Mitra S; Gera R; Linderoth B; Wahlberg LU; Darreh-Shori T; Behbahani H; Nilsson P; Eriksdotter M
  • Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2023;11(1):76
    Panahi M; Hase Y; Gallart-Palau X; Mitra S; Watanabe A; Low RC; Yamamoto Y; Sepulveda-Falla D; Hainsworth AH; Ihara M; Sze SK; Viitanen M; Behbahani H; Kalaria RN
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(16):9011
    Mitra S; Gera R; Sundheimer J; Lemee M; Wahlberg LU; Linderoth B; Eriksdotter M; Behbahani H
  • Article: CELLS. 2021;10(11):2834
    Mitra S; Turchetto S; Van Os W; Wahlberg LU; Linderoth B; Behbahani H; Eriksdotter M
  • Article: FRONTIERS IN GENETICS. 2020;11:1022
    Panahi M; Rodriguez PR; Fereshtehnejad S-M; Arafa D; Bogdanovic N; Winblad B; Cedazo-Minguez A; Rinne J; Darreh-Shori T; Hase Y; Kalaria RN; Viitanen M; Behbahani H
  • Article: CURRENT ALZHEIMER RESEARCH. 2019;16(11):1050-1054
    Jaremo P; Jejcic A; Jelic V; Shahnaz T; Oweling M; Winblad B; Behbahani H
  • Article: CURRENT ALZHEIMER RESEARCH. 2019;16(9):834-835
    Jaremo P; Jejcic A; Jelic V; Shahnaz T; Behbahani H; Oweling M; Winblad B
  • Article: MOLECULAR NEUROBIOLOGY. 2019;56(7):4601-4619
    Darreh-Shori T; Rezaeianyazdi S; Lana E; Mitra S; Gellerbring A; Karami A; Bogdanovic N; Lithner CU; Winblad B; Behbahani H
  • Article: EUROPEAN JOURNAL OF CELL BIOLOGY. 2018;97(8):557-567
    Hanemaaijer ES; Panahi M; Swaddiwudhipong N; Tikka S; Winblad B; Viitanen M; Piras A; Behbahani H
  • Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):175-184
    Eriksdotter M; Navarro-Oviedo M; Mitra S; Wahlberg L; Linderoth B; Tjernberg LO; Behbahani H
  • Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2018;22(6):3016-3024
    Panahi M; Mesri NY; Samuelsson E-B; Coupland KG; Forsell C; Graff C; Tikka S; Winblad B; Viitanen M; Karlstrom H; Sundstrom E; Behbahani H
  • Article: MOLECULAR NEUROBIOLOGY. 2017;54(2):874-887
    Lana E; Khanbolouki M; Degavre C; Samuelsson E-B; Akesson E; Winblad B; Alici E; Lithner CU; Behbahani H
  • Article: PLATELETS. 2017;28(2):182-186
    Milovanovic M; Nilsson S; Winblad B; Jelic V; Behbahani H; Shahnaz T; Oweling M; Jaremo P
  • Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;53(2):621-630
    Tajeddinn W; Fereshtehnejad S-M; Ahmed MS; Yoshitake T; Kehr J; Shahnaz T; Milovanovic M; Behbahani H; Hoglund K; Winblad B; Cedazo-Minguez A; Jelic V; Jaremo P; Aarsland D
  • Article: JOURNAL OF NEUROCHEMISTRY. 2016;136(3):497-502
    Ronnback A; Pavlov PF; Mansory M; Gonze P; Marliere N; Winblad B; Graff C; Behbahani H
  • Article: MOLECULAR NEUROBIOLOGY. 2015;52(3):1077-1092
    Lucotte B; Tajhizi M; Alkhatib D; Samuelsson E-B; Wiehager B; Schedin-Weiss S; Sundstrom E; Winblad B; Tjernberg LO; Behbahani H
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(19):7916-7921
    Hedskog L; Pinho CM; Filadi R; Ronnback A; Hertwig L; Wiehager B; Larssen P; Gellhaar S; Sandebring A; Westerlund M; Graff C; Winblad B; Galter D; Behbahani H; Pizzo P; Glaser E; Ankarcrona M
  • Article: EXPERIMENTAL CELL RESEARCH. 2013;319(3):134-143
    Viitanen M; Sundstrom E; Baumann M; Poyhonen M; Tikka S; Behbahani H
  • Article: PLOS ONE. 2013;8(6):e65936
    Vijayaraghavan S; Karami A; Aeinehband S; Behbahani H; Grandien A; Nilsson B; Ekdahl KN; Lindblom RPF; Piehl F; Darreh-Shori T
  • Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;424(3):476-481
    Teranishi Y; Hur J-Y; Gu GJ; Kihara T; Ishikawa T; Nishimura T; Winblad B; Behbahani H; Kamali-Moghaddam M; Frykman S; Tjernberg LO
  • Show more

All other publications

  • Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2021;1331:167-191
    Mitra S; Gera R; Linderoth B; Lind G; Wahlberg L; Almqvist P; Behbahani H; Eriksdotter M
  • Review: FRONTIERS IN NEUROSCIENCE. 2019;13:38
    Mitra S; Behbahani H; Eriksdotter M
  • Published conference paper: JOURNAL OF INFECTIOUS DISEASES. 2002;185(9):1355-1358
    Andersson J; Kinloch S; Sönnerborg A; Nilsson J; Fehniger TE; Spetz AL; Behbahani H; Goh LE; McDade H; Gazzard B; Stellbrink H; Cooper D; Perrin L
  • Doctoral thesis: 2002
    Behbahani H

Employments

  • Affiliated to Research, Department of Neurobiology, Care Sciences and Society, ̽ѡ, 2023-2025

Degrees and Education

  • Docent, Karolinska institutet, 2011
  • Doctor Of Philosophy, Department of Medicine, Huddinge, ̽ѡ, 2002

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