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John Inge Johnsen

John Inge Johnsen

Principal Researcher | Docent
Visiting address: Widerströmska huset, hiss 1, plan 8 Tomtebodavägen 18A, 17177 Stockholm
Postal address: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Kogner/Johnsen, 171 77 Stockholm
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About me

  • Dr. John Inge Johnsen received his PhD diploma at University of Tromsö,
    Norway under the supervision of Professor Terje Traavik in 1994. His thesis
    focused on the characterization of regulatory genetic elements in
    polyomaviruses and the effects these regulatory regions have on host/virus
    interaction.
    After finishing his PhD, Dr. Johnsen went on to pursue his main scientific
    interest; cancer biology, oncogenes and tumor suppressor genes and 1995 he
    joined Professor Eric Stanbridge´s research group at University of
    California, Irvine where he studied the effects of p53 and genes regulated by
    p53 on cancer development.
    After spending two years at the University of Tromsö as an assistant
    professor/lecturer Dr. Johnsen joined professor Per Kogner´s research group
    at ̽»¨¾«Ñ¡ as a postdoctoral fellow where he together with Dr.
    Kogner built up the childhood neural tumor research consortium.
    Dr. Johnsen became Associate professor at Karolinska Instituet in 2010.
    1984-1990 Msc, University of Tromsö, Norway
    1991-1994 PhD, University of Tromsö, Norway
    1995-1997 Postdoc, Dr.Stanbridge´s lab, University of California, Irvine,
    USA
    1997-1998 Postdoc, Dept. of Pediatrics, University of Tromsö Norway
    2001-2003 Postdoc, Childhood Cancer Research Unit, Karolinska Istitutet

Research

  • The main focus of our research group is to search for new treatment options
    that lead to better survival, less treatment-related complications and better
    quality of life for children with medulloblastoma and neuroblastoma. This is
    done by applying different Omic techniques to characterize the molecular
    landscape of malignant and corresponding non-cancerous cells within the tumor
    microenvironment and to use a translational approach applying preclinical in
    vivo models to characterize the anti-tumorigenic effects of drugs and
    compounds targeting specific biological aberrations in cancer cells or
    populations of cells located within the tumor microenvironment.

Articles

  • Article: CANCER LETTERS. 2025;625:217769
    Milosevic J; Fransson S; Svensson J; Otte J; Olsen TK; Sveinbjornsson B; Hertwig F; Bartenhagen C; Abel F; Reinsbach SE; Djos A; Javanmardi N; Shi Y; Hehir-Kwa JY; Mensenkamp A; Tytgat GAM; Holmberg J; Molenaar JJ; Jongmans M; Fischer M; Baryawno N; Gisselsson D; Martinsson T; Kogner P; Johnsen JI
  • Article: CANCER RESEARCH. 2025;85(6):1015-1034
    Embaie BT; Sarkar H; Alchahin AM; Otte J; Olsen TK; Tummler C; Kameneva P; Artemov AV; Akkuratova N; Adameyko I; Stukenborg J-B; Wickstrom M; Kogner P; Johnsen JI; Mei S; Kharchenko PV; Baryawno N
  • Article: EMBO JOURNAL. 2024;43(24):6310-6335
    Thombare K; Vaid R; Pucci P; Lundberg KI; Ayyalusamy R; Baig MH; Mendez A; Burgos-Panadero R; Hoeppner S; Bartenhagen C; Sjovall D; Rehan AA; Nale SD; Djos A; Martinsson T; Jaako P; Dong J-J; Kogner P; Johnsen JI; Fischer M; Turner SD; Mondal T
  • Article: CANCER LETTERS. 2024;605:217261
    Pepich A; Tummler C; Abu Ajamieh S; Treis D; Boje AS; Vellema Q; Tsea I; Akerlund E; Seashore-Ludlow B; Fard SS; Kogner P; Johnsen JI; Wickstrom M
  • Article: NEURO-ONCOLOGY. 2024;27(3):779-794
    van Bree N; Oppelt A-S; Lindstroem S; Zhou L; Boutin L; Coyle B; Swartling FJ; Johnsen JI; Braeutigam L; Wilhelm M
  • Journal article: CANCER RESEARCH. 2024;84(17):b060
    Verhoeven BM; Ye K; Stenman J; Kogner P; Johnsen JI; Reina OB; Kreslavskiy T; Baryawno N
  • Article: MOLECULAR CANCER. 2024;23(1):180
    Olsen TK; Otte J; Mei S; Embaie BT; Kameneva P; Cheng H; Gao T; Zachariadis V; Tsea I; Bjorklund A; Kryukov E; Hou Z; Johansson A; Sundstrom E; Martinsson T; Fransson S; Stenman J; Fard SS; Johnsen JI; Kogner P; Adameyko I; Enge M; Kharchenko PV; Baryawno N
  • Article: NUCLEIC ACIDS RESEARCH. 2024;52(5):2648-2671
    Vaid R; Thombare K; Mendez A; Burgos-Panadero R; Djos A; Jachimowicz D; Lundberg KI; Bartenhagen C; Kumar N; Tummler C; Sihlbom C; Fransson S; Johnsen JI; Kogner P; Martinsson T; Fischer M; Mondal T
  • Article: CANCERS. 2024;16(4):812
    Johnsen JI; Kogner P
  • Article: JCI INSIGHT. 2024;9(6):e173337
    Mei S; Alchahin AM; Embaie BT; Gavriliuc IM; Verhoeven BM; Zhao T; Li X; Jeffries NE; Pepich A; Sarkar H; Olsen TK; Wickstrom M; Stenman J; Reina-Bedoya O; Kharchenko PV; Saylor PJ; Johnsen JI; Sykes DB; Kogner P; Baryawno N
  • Article: GENOME MEDICINE. 2024;16(1):1
    Mei S; Alchahin AM; Tsea I; Kfoury Y; Hirz T; Jeffries NE; Zhao T; Xu Y; Zhang H; Sarkar H; Wu S; Subtelny AO; Johnsen JI; Zhang Y; Salari K; Wu C-L; Randolph MA; Scadden DT; Dahl DM; Shin J; Kharchenko PV; Saylor PJ; Sykes DB; Baryawno N
  • Journal article: NEURO-ONCOLOGY ADVANCES. 2024;6(1):vdae172
    Ruchiy Y; Tsea I; Preka E; Verhoeven BM; Olsen TK; Mei S; Sinha I; Blomgren K; Carlson L-M; Dyberg C; Johnsen JI; Baryawno N
  • Article: NEURO-ONCOLOGY ADVANCES. 2024;6(1):vdae172
    Ruchiy Y; Tsea I; Preka E; Verhoeven BM; Olsen TK; Mei S; Sinha I; Blomgren K; Carlson L-M; Dyberg C; Johnsen JI; Baryawno N
  • Article: CANCERS. 2023;15(18):4599
    Yuan Y; Alzrigat M; Rodriguez-Garcia A; Wang X; Bexelius TS; Johnsen JI; Arsenian-Henriksson M; Liano-Pons J; Bedoya-Reina OC
  • Journal article: NEURO-ONCOLOGY. 2023;25(Suppl 1):i62
    MDB-04. SINGLE-CELL TRANSCRIPTOMIC ANALYSIS REVEALS DISTINCT GENOMIC LANDSCAPES, CELL TRAJECTORIES, AND TUMOUR-MICROENVIRONMENT INTERACTIONS IN FOUR SUBTYPES OF MEDULLOBLASTOMA
  • Article: BRITISH JOURNAL OF CANCER. 2022;127(11):2060-2071
    Zhou X; Santos GS; Zhan Y; Oliveira MMS; Rezaei S; Singh M; Peuget S; Westerberg LS; Johnsen JI; Selivanova G
  • Article: JCI INSIGHT. 2022;7(17):e153836
    Olsen TK; Dyberg C; Embaie BT; Alchahin A; Milosevic J; Ding J; Otte J; Tummler C; Myrberg IH; Westerhout EM; Koster J; Versteeg R; Ding H-F; Kogner P; Johnsen JI; Sykes DB; Baryawno N
  • Article: CELL REPORTS MEDICINE. 2022;3(6):100657
    Verhoeven BM; Mei S; Olsen TK; Gustafsson K; Valind A; Lindstrom A; Gisselsson D; Fard SS; Hagerling C; Kharchenko PV; Kogner P; Johnsen JI; Baryawno N
  • Journal article: CANCER RESEARCH. 2022;82(12_Supplement):1677
    Tsea I; Ruchiy Y; Verhoeven M; Sinha I; Blomgren K; Carlson LM; Johnsen JI; Dyberg C; Baryawno N
  • Journal article: CANCER RESEARCH. 2022;82(12_Supplement):6215
    Verhoeven BM; Mei S; Olsen TK; Gustafsson KK; Valind A; Lindström A; Nord DG; Fard SS; Hagerling C; Kharchenko PV; Kogner P; Johnsen JI; Baryawno N
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Employments

  • Principal Researcher, Department of Women's and Children's Health, ̽»¨¾«Ñ¡, 2022-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2010

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