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Katsuhiko Shirahige

Katsuhiko Shirahige

Visiting Professor
Visiting address: Solnavägen 9, 17165 Stockholm
Postal address: C5 Cell- och molekylärbiologi, C5 CMB Björkegren, 171 77 Stockholm

About me

  • Katsuhiko Shirahige is Visiting Professor of Cell and Molecular Biology, Quantitative Analysis of Chromosome Function at the Department of Cell and Molecular Biology, as of 1 March 2024. He is also a Professor and Director at the Institute for Quantitative Biosciences, Tokyo University, Japan. 

    Katsuhiko Shirahige researches chromosome dynamics, gene expression and gene regulation. It is well-known that genes interact with other regions along the chromosome, and that these interactions can influence gene expression by “raising” or “lowering” it. Professor Shirahige’s research focuses on cohesin, a protein complex that controls these interactions by folding the chromosome in three-dimensional space. Cohesin mutations are known to cause cancer and developmental defects in the embryo. The aim of Katsuhiko Shirahige’s studies is to improve understanding of these diseases at a molecular level, thereby paving the way for new drugs.

Articles

  • Article: ISCIENCE. 2025;28(5):112322
    Nguyen SA; Sakata T; Shirahige K; Sutani T
  • Article: CURRENT BIOLOGY. 2025;35(6):1353-1363.e5
    Sakata T; Tei S; Izumi K; Krantz ID; Bando M; Shirahige K
  • Article: MOLECULAR CELL. 2024;84(5):867-882.e5
    Jeppsson K; Pradhan B; Sutani T; Sakata T; Igarashi MU; Berta DG; Kanno T; Nakato R; Shirahige K; Kim E; Bjorkegren C
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(5):2540
    Fukuda M; Fujita Y; Hino Y; Nakao M; Shirahige K; Yamashita T
  • Article: LIFE SCIENCE ALLIANCE. 2024;7(1):e202302077
    Homma MK; Nakato R; Niida A; Bando M; Fujiki K; Yokota N; Yamamoto S; Shibata T; Takagi M; Yamaki J; Kozuka-Hata H; Oyama M; Shirahige K; Homma Y
  • Article: NATURE COMMUNICATIONS. 2023;14(1):5647
    Nakato R; Sakata T; Wang J; Nagai LAE; Nagaoka Y; Oba GM; Bando M; Shirahige K
  • Article: SCIENCE ADVANCES. 2022;8(23):eabn7063
    Jeppsson K; Sakata T; Nakato R; Milanova S; Shirahige K; Bjorkegren C
  • Article: NATURE COMMUNICATIONS. 2022;13(1):3218
    Wang J; Bando M; Shirahige K; Nakato R
  • Article: CANCER DISCOVERY. 2020;10(6):836-853
    Ochi Y; Kon A; Sakata T; Nakagawa MM; Nakazawa N; Kakuta M; Kataoka K; Koseki H; Nakayama M; Morishita D; Tsuruyama T; Saiki R; Yoda A; Okuda R; Yoshizato T; Yoshida K; Shiozawa Y; Nannya Y; Kotani S; Kogure Y; Kakiuchi N; Nishimura T; Makishima H; Malcovati L; Yokoyama A; Takeuchi K; Sugihara E; Sato T-A; Sanada M; Takaori-Kondo A; Cazzola M; Kengaku M; Miyano S; Shirahige K; Suzuki HI; Ogawa S

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