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Lara Kular

Lara Kular

Senior Research Specialist
Visiting address: L8:05, CMM Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Jagodic Kular, 171 77 Stockholm

About me

  • I am Team Leader in Maja Jagodic's group of the Karolinska Neuroimmunology and Multiple Sclerosis (KNIMS) network.

     

    Grants: the Swedish Research Council (VetenskapsrÃ¥det), The Swedish Brain Foundation (Hjärnfonden), the Swedish Association for Persons with Neurological Disabilities (Neuroförbundet), the Swedish MS Foundation (MS Forskningsfonden), The Norlins Foundation, Magnus Bergvalls Foundation, Petrus och Augusta Hedlunds  Foundation, Ã…ke Wiberg Foundation, Margaretha af Ugglas Foundation, ̽»¨¾«Ñ¡ Research Foundation.


    Short bio: I have a PhD in Human Physiology and Physiopathology (highest honours), Pierre et Marie Curie University (UPMC – Sorbonne Universités), Sept 2011, Paris,  France. Before that, I obtained a Research Master in Physiology and Physiopathology (/cum laude/), Rennes 1 
    University, June 2007, Rennes, France and an Engineering Degree in Life Science, ENSAR, July 2007, France.

Research

  • I aim to exploit the /potential of epigenetics to better understand and treat neuroinflammatory and neurodegenerative disorders, with a focus on Multiple Sclerosis disease. I have a particular interest in unraveling the molecular mechanisms along the lung-brain axis that underlie the impact of smoking in disease development and severity. By integrating state-of-art methodological and causal approaches in molecular, cellular and experimental neuroscience into a clinical framework, I hope to fully translate novel knowledge into clinical applications, with the prospect to potentially /revolutionize translational research and personalized medicine. My expertise relies on robust theoretical and practical knowledge in in-vivo studies of models of neuropathology as well as diverse molecular and cellular skills in epigenetics and neuroscience that I acquired during my career. In a word, my scientific ambition is driven by a rooted passion for epigenetics and ever-growing motivation to unravel its potential in clinical neuroscience. My research is embedded in a highly collaborative and dynamic research center: Karolinska Neuroimmunology and Multiple Sclerosis (KNIMS) network. 

Articles

  • Article: EBIOMEDICINE. 2024;110:105470
    Lewandowski SA; Kular L; Jagodic M
  • Article: NATURE COMMUNICATIONS. 2024;15(1):6419
    Kakhki MP; Giordano A; Cucuzza CS; Badam TVS; Samudyata S; Lemee MV; Stridh P; Gkogka A; Shchetynsky K; Harroud A; Gyllenberg A; Liu Y; Boddul S; James T; Sorosina M; Filippi M; Esposito F; Wermeling F; Gustafsson M; Casaccia P; Hillert J; Olsson T; Kockum I; Sellgren CM; Golzio C; Kular L; Jagodic M
  • Article: BRAIN, BEHAVIOR, & IMMUNITY - HEALTH. 2024;38:100787
    Kular L
  • Article: ACTA NEUROPATHOLOGICA. 2024;147(1):82
    Windener F; Grewing L; Thomas C; Dorion M-F; Otteken M; Kular L; Jagodic M; Antel J; Albrecht S; Kuhlmann T
  • Article: NATURE IMMUNOLOGY. 2024;25(3):432-447
    Linnerbauer M; Loesslein L; Vandrey O; Peter A; Han Y; Tsaktanis T; Wogram E; Needhamsen M; Kular L; Nagel L; Zissler J; Andert M; Meszaros L; Hanspach J; Zuber F; Naumann UJ; Diebold M; Wheeler MA; Beyer T; Nirschl L; Cirac A; Laun FB; Guenther C; Winkler J; Baeuerle T; Jagodic M; Hemmer B; Prinz M; Quintana FJ; Rothhammer V
  • Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2023;79:104991
    Klose D; Needhamsen M; Ringh MV; Hagemann-Jensen M; Jagodic M; Kular L
  • Article: NEUROLOGY. 2023;101(7):e679-e689
    Maltby V; Xavier A; Ewing E; Campagna M-P; Sampangi S; Scott RJ; Butzkueven H; Jokubaitis V; Kular L; Bos S; Slee M; van der Mei IA; Taylor BV; Ponsonby A-L; Jagodic M; Lea R; Lechner-Scott J
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(16):12576
    Xavier A; Maltby VE; Ewing E; Campagna MP; Burnard SM; Tegner JN; Slee M; Butzkueven H; Kockum I; Kular L; Jokubaitis VG; Kilpatrick T; Alfredsson L; Jagodic M; Ponsonby A-L; Taylor BV; Scott RJ; Lea RA; Lechner-Scott J
  • Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2023;160:217-224
    Bostrom AED; Jamshidi E; Manu D-M; Kular L; Schioth HB; Asberg M; Jokinen J
  • Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1251772
    Kalomoiri M; Prakash CR; Lagstroem S; Hauschulz K; Ewing E; Shchetynsky K; Kular L; Needhamsen M; Jagodic M
  • Article: EPIGENETICS. 2022;17(11):1311-1330
    Kular L; Ewing E; Needhamsen M; Kakhki MP; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
  • Article: FRONTIERS IN AGING NEUROSCIENCE. 2022;14:926468
    Kular L; Klose D; Urdanoz-Casado A; Ewing E; Planell N; Gomez-Cabrero D; Needhamsen M; Jagodic M
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026
    Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom TJ; Ockinger J; Kular L
  • Article: CLINICAL EPIGENETICS. 2020;12(1):99
    Ciuculete DM; Voisin S; Kular L; Jonsson J; Rask-Andersen M; Mwinyi J; Schioth HB
  • Article: EPIGENETICS. 2020;15(6-7):646-663
    Ciuculete DM; Voisin S; Kular L; Welihinda N; Jonsson J; Jagodic M; Mwinyi J; Schioth HB
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(2):838-852
    N'diaye M; Brauner S; Flytzani S; Kular L; Warnecke A; Adzemovic MZ; Piket E; Min J-H; Edwards W; Mela F; Choi HY; Magg V; James T; Linden M; Reichardt HM; Daws MR; van Horssen J; Kockum I; Harris RA; Olsson T; Guerreiro-Cacais AO; Jagodic M
  • Article: EBIOMEDICINE. 2019;46:290-304
    Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjoholm LK; Slavec L; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Ockinger J; Ekstrom TJ
  • Article: JOURNAL OF AUTOIMMUNITY. 2019;101:17-25
    Piket E; Zheleznyakova GY; Kular L; Jagodic M
  • Article: CLINICAL EPIGENETICS. 2019;11(1):86
    Kular L; Needhamsen M; Adzemovic MZ; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegner J; Beck S; Piehl F; Brundin L; Jagodic M
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(19):9443-9452
    Li D; Kular L; Vij M; Herter EK; Li X; Wang A; Chu T; Toma M-A; Zhang L; Liapi E; Mota A; Blomqvist L; Serezal IG; Rollman O; Wikstrom JD; Bienko M; Berglund D; Stahle M; Sommar P; Jagodic M; Landen NX
  • Article: EBIOMEDICINE. 2019;43:411-423
    Ewing E; Kular L; Fernandes SJ; Karathanasis N; Lagani V; Ruhrmann S; Tsamardinos I; Tegner J; Piehl F; Gomez-Cabrero D; Jagodic M
  • Article: NATURE COMMUNICATIONS. 2018;9(1):4845
    Lund H; Pieber M; Parsa R; Han J; Grommisch D; Ewing E; Kular L; Needhamsen M; Espinosa A; Nilsson E; Overby AK; Butovsky O; Jagodic M; Zhang X-M; Harris RA
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2018;24(10):1288-1300
    Ruhrmann S; Ewing E; Piket E; Kular L; Lorenzi JCC; Fernandes SJ; Morikawa H; Aeinehband S; Sayols-Baixeras S; Aslibekyan S; Absher DM; Arnett DK; Tegner J; Gomez-Cabrero D; Piehl F; Jagodic M
  • Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2018;102:44-51
    Ciuculete DM; Bostrom AE; Tuunainen A-K; Sohrabi F; Kular L; Jagodic M; Voisin S; Mwinyi J; Schioth HB
  • Article: NATURE COMMUNICATIONS. 2018;9(1):2397
    Kular L; Liu Y; Ruhrmann S; Zheleznyakova G; Marabita F; Gomez-Cabrero D; James T; Ewing E; Linden M; Gornikiewicz B; Aeinehband S; Stridh P; Link J; Andlauer TFM; Gasperi C; Wiendl H; Zipp F; Gold R; Tackenberg B; Weber F; Hemmer B; Strauch K; Heilmann-Heimbach S; Rawal R; Schminke U; Schmidt CO; Kacprowski T; Franke A; Laudes M; Dilthey AT; Celius EG; Sondergaard HB; Tegner J; Harbo HF; Oturai AB; Olafsson S; Eggertsson HP; Halldorsson BV; Hjaltason H; Olafsson E; Jonsdottir I; Stefansson K; Olsson T; Piehl F; Ekstroem TJ; Kockum I; Feinberg AP; Jagodic M
  • Article: NATURE IMMUNOLOGY. 2018;19(5):1-7
    Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
  • Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(4):882-892
    Lohcharoenkal W; Das Mahapatra K; Pasquali L; Crudden C; Kular L; Ulum YZA; Zhang L; Landen NX; Girnita L; Jagodic M; Stahle M; Sonkoly E; Pivarcsi A
  • Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(6):479-485
    Ghafelehbashi H; Kakhki MP; Kular L; Moghbelinejad S; Ghafelehbashi SH
  • Article: BMC BIOINFORMATICS. 2017;18(1):486
    Needhamsen M; Ewing E; Lund H; Gomez-Cabrero D; Harris RA; Kular L; Jagodic M
  • Article: SCIENTIFIC REPORTS. 2017;7(1):14589
    Marabita F; Almgren M; Sjoholm LK; Kular L; Liu Y; James T; Kiss NB; Feinberg AP; Olsson T; Kockum I; Alfredsson L; Ekstrom TJ; Jagodic M
  • Article: JOURNAL OF IMMUNOLOGY. 2013;190(8):4066-4075
    Bergman P; James T; Kular L; Ruhrmann S; Kramarova T; Kvist A; Supic G; Gillett A; Pivarcsi A; Jagodic M
  • Article: JOURNAL OF NEUROINFLAMMATION. 2012;9:36
    Kular L; Rivat C; Lelongt B; Calmel C; Laurent M; Pohl M; Kitabgi P; Melik-Parsadaniantz S; Martinerie C
  • Article: GLIA. 2010;58(12):1510-1521
    Le Dréau G; Kular L; Nicot AB; Calmel C; Melik-Parsadaniantz S; Kitabgi P; Laurent M; Martinerie C
  • Show more

All other publications

  • Review: JOURNAL OF INTERNAL MEDICINE. 2020;288(1):82-102
    Kular L; Jagodic M
  • Review: EVOLUTION PSYCHIATRIQUE. 2019;84(1):207-221
    Kular S; Kular L
  • Review: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2018;72(4):195-211
    Kular L; Kular S
  • Corrigendum: SCIENTIFIC REPORTS. 2018;8(1):4340
    Marabita F; Almgren M; Sjoholm LK; Kular L; Liu Y; James T; Kiss NB; Feinberg AP; Olsson T; Kockum I; Alfredsson L; Ekstrom TJ; Jagodic M
  • Review: PHYSIOLOGICAL GENOMICS. 2017;49(9):447-461
    Zheleznyakova GY; Piket E; Marabita F; Kakhki MP; Ewing E; Ruhrmann S; Needhamsen M; Jagodic M; Kular L
  • Review: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 2015;67:49-57
    Ruhrmann S; Stridh P; Kular L; Jagodic M
  • Review: BIOCHIMIE. 2011;93(3):377-388
    Kular L; Pakradouni J; Kitabgi P; Laurent M; Martinerie C
  • Review: FRONTIERS IN NEUROENDOCRINOLOGY. 2011;32(1):10-24
    Rostène W; Guyon A; Kular L; Godefroy D; Barbieri F; Bajetto A; Banisadr G; Callewaere C; Conductier G; Rovère C; Mélik-Parsadaniantz S; Florio T

Grants

  • Swedish Research Council
    1 January 2022 - 31 December 2025

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