̽»¨¾«Ñ¡

Marcus Skribek

Marcus Skribek

Affiliated to Research
Visiting address: J6:20 BioClinicum, Akademiska stråket 1, 17164 Solna
Postal address: K7 Onkologi-Patologi, K7 Forskning Ekman, 171 77 Stockholm

About me

  • I am a Clinical Oncologist at Karolinska University Hospital and a Postdoctoral Fellow at the Department of Oncology-Pathology at ̽»¨¾«Ñ¡, with a focus on improving outcomes for patients with lung cancer.

     

    My work spans translational research, registry-based real-world evidence, and clinical trial development. I serve as Principal Investigator and Co-Investigator in national and international trials and lead projects on treatment sequencing, brain metastases, toxicity, corticosteroid use, predictive modeling, and more. I have co-developed clinical tools to support therapeutic decision-making and improve survival in real-world settings.

     

    Previously, I served as Acting Head of the Lung Cancer Section, leading one of Sweden’s highest-volume thoracic oncology units. I am also engaged in international academic collaborations and have contributed to clinical guidelines, oncology education, and high-impact publications.

     

    My goal is to integrate clinical insight with data-driven innovation to advance personalized care, inform drug development, and improve outcomes for patients with thoracic malignancies globally.

Research

  • My research focuses on advancing thoracic oncology through translational science, real-world evidence, and applied analytics. As a clinical oncologist, I bring a patient-centered perspective to research, ensuring that scientific questions and outcomes are grounded in clinical relevance and real-world impact.

     

    My work spans treatment resistance, brain metastases, immunotherapy, comedications, and toxicity management in non-small cell lung cancer (NSCLC). I lead and collaborate on studies using national registry data, retrospective cohorts, and clinical trial datasets to explore predictive biomarkers, treatment sequencing strategies, and health outcomes.

     

    I have developed and validated clinical tools and prognostic models that support therapeutic decision-making in daily practice. My expertise includes multivariable modeling, survival analysis, propensity score methods, and integration of findings into multidisciplinary clinical care.

     

    I serve as Principal and Co-Investigator in national and international clinical trials, and my ongoing projects include investigations of corticosteroid impact on ICI outcomes, intracranial response dynamics, and optimized therapy for CNS-involved NSCLC—with the goal of personalizing treatment and improving survival and quality of life for patients.

Teaching

  • I am actively engaged in ̽»¨¾«Ñ¡ education, with experience across academic, clinical, and research-based teaching:

    • Seminar leader in oncology and cancer biology, including targeted therapies and immuno-oncology.
    • Clinical supervisor for ̽»¨¾«Ñ¡ students and junior doctors in oncology rotations at Karolinska University Hospital.
    • Research supervisor in Ekman’s lab, mentoring ̽»¨¾«Ñ¡ students, PhD candidates, and clinical researchers on translational and real-world data projects.
    • Former coordinator of resident education in oncology, responsible for designing and delivering structured seminar series and clinical teaching programs.
    • Author of local clinical guidelines for the use of hematopoietic growth factors in patients with solid tumors.
    • Peer reviewer for multiple high-impact international journals in oncology and translational medicine.

Articles

  • Article: LUNG CANCER. 2025;199:108065
    Zerdes I; Kamali C; Johannsdottir B; Blasi M; Assmann C; Kazdal D; Stenzinger A; Skribek M; Ekman S; Christopoulos P; Tsakonas G
  • Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2024;74(1):14
    Ladjevardi CO; Skribek M; Koliadi A; Ryden V; El-Naggar AI; Digkas E; Valachis A; Ullenhag GJ
  • Journal article: ANNALS OF ONCOLOGY. 2024;35:s858
    Koulouris AV; Skribek MC; Kamali C; Grundberg O; Lampa E; Gubanski M; Hydbring P; Ekman S; Tsakonas G
  • Article: EUROPEAN JOURNAL OF RADIOLOGY. 2024;177:111557
    Grundberg O; Skribek M; Swerkersson S; Skorpil M; Kolbeck K; Grozman V; Nyren S; Tsakonas G
  • Article: ACTA ONCOLOGICA. 2023;62(12):1808-1814
    Skribek M; Brunnstrom H; Oskarsdottir G; Grive MP; Aricak O; Planck M; Jatta K; Naserhojati H; de Flon FH; Ekman S
  • Journal article: JOURNAL OF THORACIC ONCOLOGY. 2023;18(11):s638
    Skribek M; Sierakowiak A; Koulouris A; Rounis K; Goenechea J; Labor M; Lund HW; Axelsson I; Fornwall A; Tsakonas G; Koyi H
  • Article: LUNG CANCER. 2022;166:132-134
    Skribek M; Bozoky B; Tsakonas G
  • Article: CANCERS. 2021;13(7):1562
    Rounis K; Skribek M; Makrakis D; De Petris L; Agelaki S; Ekman S; Tsakonas G
  • Article: EUROPEAN JOURNAL OF CANCER. 2021;145:245-254
    Skribek M; Rounis K; Afshar S; Grundberg O; Friesland S; Tsakonas G; Ekman S; De Petris L
  • Article: CANCERS. 2020;12(12):E3707-3707
    Skribek M; Rounis K; Makrakis D; Agelaki S; Mavroudis D; De Petris L; Ekman S; Tsakonas G

All other publications

  • Review: CANCERS. 2025;17(6):986
    Zipprick J; Demir E; Krynska H; Kopruluoglu S; Strauss K; Skribek M; Otvos RH-G; Gad AKB; Dobra K
  • Thesis / dissertation: KAROLINSKA INSTITUTET. 2024
    Skribek M
  • Doctoral thesis: 2024
    Skribek M
  • Thesis / dissertation: KAROLINSKA INSTITUTET. 2024
    Skribek M
  • Preprint: MEDRXIV. 2024
    Skribek M; Livanou M-E; Vathiotis I; Strandman V; Thorell A; Koulouris A; Syrigos K; Ekman S; Tsakonas G
  • Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2023;18(11):s599
    Tsakonas G; Skribek M; Kamali C; Zerdes I; Jóhannsdóttir B; Ekman S
  • Review: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(3):e005841
    Liu LL; Skribek M; Harmenberg U; Gerling M
  • Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2023;18(11):S638
    Skribek M; Sierakowiak A; Koulouris A; Rounis K; Goenechea J; Labor M; Lund HW; Axelsson I; Fornwall A; Tsakonas G; Koyi H
  • Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2023;18(11):S599
    Tsakonas G; Skribek M; Kamali C; Zerdes I; Johannsdottir B; Ekman S
  • Conference publication: ANNALS OF ONCOLOGY. 2022;33(7):S1087
    Skribek M; Brunnstrom H; Aricak O; Planck M; Jatta K; Oskarsdottir GN; Naserhojati H; Haglund F; Ekman S
  • Preprint: MEDRXIV. 2022
    Liu L; Skribek M; Harmenberg U; Gerling M
  • Review: JOURNAL OF INTERNAL MEDICINE. 2022;291(6):732-754
    Skribek M; Rounis K; Tsakonas G; Ekman S

Grants

  • Research Grant
    The Cancer Research Funds of Radiumhemmet
    1 June 2022 - 31 May 2024

Employments

  • Affiliated to Research, Department of Oncology-Pathology, ̽»¨¾«Ñ¡, 2023-2026

Visiting research fellowships

  • Clinical Research Fellow, Memorial Sloan Kettering Cancer Center, - Joined MSKCC to deepen expertise in oncology through firsthand learning of cancer management and treatment practices. - Collaborated with multidisciplinary teams to enhance patient outcomes and advance cancer care methodologies. - Specialized in radiotheranostics at the Jason Lewis Lab, integrating diagnostic imaging and targeted therapy to develop precision medicine approaches. - Involved in research focusing on DLL3 in small cell lung cancer and DLK1 in sarcoma, aiming to develop effective therapies for aggressive cancer types. - Worked under the supervision of industry-leading experts to pioneer novel cancer therapy methods., 2024-2024

News from KI

Events from KI