̽»¨¾«Ñ¡

Mattias Carlsten

Mattias Carlsten

Affiliated to Research | Docent
Visiting address: ,
Postal address: H5 Laboratoriemedicin, H5 BCM Carlsten, 171 77 Stockholm
Part of:

About me

  • I received my MD degree from ̽»¨¾«Ñ¡ 2007 after conducting
    studies within the MD/PhD program. Following completion of my ̽»¨¾«Ñ¡
    intership (Forskar-AT) at the Karolinska University Hospital late fall 2009,
    I defended my PhD thesis at ̽»¨¾«Ñ¡ early spring 2010
    supervised by Prof. Karl-Johan Malmbergs and Prof. Rolf Kiessling. I then
    joined the group of Dr. Richard W. Childs at Hematology Branch, NHLBI, NIH
    (USA) as a Postdoc 2010. Since 2012 I have been doing my residency/fellowship
    in Internal Medicine/Hematology at Center for Hematology, Karolinska
    University Hospital, with the exception of a sabatical between 2013-2015 when
    I was employed as a Staff Scientist with Dr. Childs at the NIH. From 2016, I
    am a Research Group leader at Center for Regenerative Medicine and
    Hematology (HERM), Department of Medicine Huddinge, ̽»¨¾«Ñ¡.
    2015, SSMF Stora Anslag
    2015, Jeanssons Stiftelser Personal Achievement Award
    2012, Translational Research Training in Hematology (TRTH) Award
    2010, Dean O’Neill Renal Cancer Cell Research Fellowship
    2004, MD/PhD program at ̽»¨¾«Ñ¡
    2000, Läkarutbildningen med forskningsinriktning (LäFo), Karolinska
    Institutet
    2007, MD, ̽»¨¾«Ñ¡
    2009, Swedish Medical Practioner License, Karolinska University Hospital
    2010, PhD, ̽»¨¾«Ñ¡
    2010-2012, Postdoctoral Fellow, Hematology Branch, NHLBI, NIH
    2013-2015, Staff Scientist, Hematology Branch, NHLBI, NIH
    2012-, Resident/Fellow in Internal Medicine/Hematology, Karolinska University
    Hospital
    2016-, Research Group Leader, HERM, Department of Medicine Huddinge,
    ̽»¨¾«Ñ¡

Research

  • My research focuses on cancer immunotherapy, with a particular focus on how
    NK cells can be used to treat cancer. With my experience in bench science and
    clinical medicine, my projects spans from preclinical basic NK cell biology
    and tumor immunology studies to translational to early phase clinical trials
    on NK cell-based cancer immunotherapy and stem cell transplantation. A big
    focus in my lab is currently how genetic engineering of lymphocytes,
    including NK cells, can be used to further improve the efficacy of cellular
    cancer immunotherapies.

Articles

  • Article: GUT. 2025;74(7):1125-1136
    Maravelia P; Yao H; Cai C; Silva DN; Fransson J; Nilsson OB; Lu Y-CW; Micke P; Botling J; Gatto F; Rovesti G; Carlsten M; Sallberg M; Stal P; Jorns C; Buggert M; Pasetto A
  • Journal article: HEMASPHERE. 2025;9(6):e70160
    Carlsten M; Lindfors Rossi EL; Jädersten M; Tesi B; Abd Own S; Sander B; Deneberg S; Ivinskiy A; Sonnevi K; Sjölund H; Enblad G; Wahlin B; Mielke S
  • Article: CURRENT PROTOCOLS. 2024;4(11):e70040
    Ingegnere T; Segain B; Cozzani A; Carlsten M; Mitra S; Gaggero S
  • Article: MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 2024;32(2):101225
    Al-Saadi J; Walden M; Sandell M; Sohlmer J; Grankvist R; Friberger I; Andersson A; Carlsten M; Chien K; Lundberg J; Witman N; Holmin S
  • Journal article: CYTOTHERAPY. 2024;26(6):s206
    Al-Saadi J; Walden M; Sohlmer J; Grankvist R; Friberger I; Andersson A; Lovljung V; Settergren M; Carlsten M; Chien K; Lundberg J; Witman N; Holmin S
  • Article: NPJ PRECISION ONCOLOGY. 2024;8(1):108
    Sanz-Ortega L; Leijonhufvud C; Schoutens L; Lambert M; Levy E; Andersson A; Wahlin BE; Carlsten M
  • Article: LEUKEMIA. 2024;38(3):579-589
    Sanz-Ortega L; Andersson A; Carlsten M
  • Article: JOURNAL OF IMMUNOLOGY. 2024;212(5):868-880
    Leijonhufvud C; Sanz-Ortega L; Schlums H; Gaballa A; Andersson A; Eriksson C; Segerberg F; Uhlin M; Bryceson YT; Carlsten M
  • Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:108673
    Friberger I; Tran T; Lu L; Milton S; Samen E; Goos J; Carlsten M; Holmin S
  • Article: EJNMMI RESEARCH. 2023;13(1):73
    Friberger I; Nilsson JNN; Lu L; Siikanen J; Ardenfors O; Milton S; Samen E; Goos JACM; Carlsten M; Holmin S; Tran TAA
  • Article: LEUKEMIA. 2023;37(9):1830-1841
    Palau A; Segerberg F; Lidschreiber M; Lidschreiber K; Naughton AJ; Needhamsen M; Jung LA; Jagodic M; Cramer P; Lehmann S; Carlsten M; Lennartsson A
  • Article: HAEMATOLOGICA. 2022;107(8):1786-1795
    Arruda LCM; Stikvoort A; Lambert M; Jin L; Rivera LS; Alves RMP; de Moura TR; Mim C; Lehmann S; Axelsson-Robertson R; Dick JE; Mattsson J; Onfelt B; Carlsten M; Uhlin M
  • Article: BLOOD ADVANCES. 2022;6(11):3352-3366
    Daly J; Sarkar S; Natoni A; Stark JC; Riley NM; Bertozzi CR; Carlsten M; O'Dwyer ME
  • Article: VIRCHOWS ARCHIV. 2022;480(3):655-666
    Merrien M; Wasik AM; Ljung E; Morsy MHA; Rodrigues JDM; Carlsten M; Rassidakis GZ; Christensson B; Kolstad A; Jerkeman M; Ek S; Herold N; Wahlin BE; Sander B
  • Article: MOLECULAR IMAGING AND BIOLOGY. 2021;23(6):952-962
    Friberger I; Jussing E; Han J; Goos JACM; Siikanen J; Kaipe H; Lambert M; Harris RA; Samen E; Carlsten M; Holmin S; Tran TA
  • Journal article: BRITISH JOURNAL OF HAEMATOLOGY. 2021;193(5):951-960
    Childs RW; Tian X; Vo P; Purev E; Kotecha RR; Carlsten M; Clara J; Flegel WA; Adams SD; Khuu HM; Stroncek DF; Cook L; Worthy T; Geller NL; Wells B; Wilder J; Reger R; Aue G
  • Article: BMC CANCER. 2021;21(1):500
    Noring K; Carlsten M; Sonnevi K; Wahlin BE
  • Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(10):e1346
    Leijonhufvud C; Reger R; Segerberg F; Theorell J; Schlums H; Bryceson YT; Childs RW; Carlsten M
  • Article: METHODS IN MOLECULAR BIOLOGY. 2020;2121:213-239
    Lambert M; Leijonhufvud C; Segerberg F; Melenhorst JJ; Carlsten M
  • Journal article: BLOOD. 2019;134(Supplement_1):138
    Daly J; Sarkar S; Natoni A; Henderson R; Swan D; Carlsten M; O'Dwyer ME
  • Show more

All other publications

  • Letter: HEMASPHERE. 2025;9(6):e70160
    Carlsten M; Lindfors Rossi EL; Jaedersten M; Tesi B; Abd Own S; Sander B; Deneberg S; Ivinskiy A; Sonnevi K; Sjoelund H; Enblad G; Wahlin B; Mielke S
  • Conference publication: 2024;:a496
    Gafvelin G; Joly A-L; Berglund S; Maitre EL; Urbonaviciute V; Day K; Notari L; Nilsson O; Kaiser A; Carvalho-Queiroz C; Bylund K; Woodbridge AF; Akpinar B; Jiang L; Kordes M; Carlsten M; Nikberg M; Tarfy AS; Chabok A; Salmén A; Svensson S; Xie H; Grönlund H
  • Conference publication: 2023;:a736
    Berglund S; Joly A-L; Maitre EL; Day K; Notari L; Carvalho-Queiroz C; Nilsson O; Kaiser A; Kordes M; Yachnin J; Carlsten M; Mielke S; Chabok A; Nikberg M; Tarfy AS; Salmén A; Svensson S; Xie H; Gafvelin G; Grönlund H
  • Conference publication: 2023;:a471
    Ortega LS; Andersson A; Carlsten M
  • Letter: HEMASPHERE. 2023;7(11):e974
    Segerberg F; Lambert M; Sanz-Ortega L; Andersson A; Childs RW; Carlsten M
  • Editorial comment: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2023;8(1):316
    Carlsten M; Bryceson YT
  • Conference publication: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201:114-115
    Schoutens L; Sanz-Ortega L; Leijonhufvud C; Lambert M; Levy E; Andersson A; Wahlin B; Carlsten M
  • Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:S212-S213
    Friberger I; Thuy T; Lu L; Milton S; Samen E; Goos J; Carlsten M; Holmin S
  • Conference publication: BLOOD. 2022;140:8350
    Leijonhufvud C; Schlums H; Stikvoort A; Uhlin M; Bryceson YT; Carlsten M
  • Corrigendum: MOLECULAR IMAGING AND BIOLOGY. 2022;24(3):510
    Friberger I; Jussing E; Han J; Goos JACM; Siikanen J; Kaipe H; Lambert M; Harris RA; Samen E; Carlsten M; Holmin S; Tran TA
  • Meeting abstract: BLOOD. 2021;138:2861
    Arruda LCM; Jin L; Lambert M; Rivera LS; Alvez R; de Moura TR; Mim C; Axelsson-Robertson R; Dick JE; Mattsson J; Onfelt B; Carlsten M; Uhlin M
  • Review: FRONTIERS IN IMMUNOLOGY. 2021;11:621225
    Gaggero S; Witt K; Carlsten M; Mitra S
  • Preprint: RESEARCH SQUARE. 2020
    Noring K; Carlsten M; Sonnevi K; Wahlin B
  • Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2357
    Carlsten M; Jaras M
  • Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019;19(10):E159-E160
    Daly J; Sarkar S; Natoni A; Henderson R; Swan D; Carlsten M; O'Dwyer M
  • Review: FRONTIERS IN IMMUNOLOGY. 2019;10:1047
    Daly J; Carlsten M; O'Dwyer M
  • Preprint: SSRN ELECTRONIC JOURNAL. 2018
    Carlsten M; Jädersten M; Hellström A; Littmann K; Melén CM; Junlén HR; Sonnevi K; Ljungman P; Björkstrand B; Wahlin B
  • Conference publication: BLOOD. 2017;130
    Bjorklund AT; Carlsten M; Sohlberg E; Clancy T; Liu L; Karimi M; Cooley S; Miller JS; Watz E; Wahlin BE; Palma M; Hansson L; Ljungman P; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
  • Review: SEMINARS IN IMMUNOLOGY. 2017;31:20-29
    Malmberg K-J; Carlsten M; Bjorklund A; Sohlberg E; Bryceson YT; Ljunggren H-G
  • Conference publication: BONE MARROW TRANSPLANTATION. 2016;51:S97-S98
    Bjorklund AT; Carlsten M; Sohlberg E; Liu L; Schaffer M; Watz E; Ljungman P; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
  • Show more

Employments

  • Affiliated to Research, Department of Laboratory Medicine, ̽»¨¾«Ñ¡, 2024-2027
  • Principal Researcher, Department of Laboratory Medicine, ̽»¨¾«Ñ¡, 2025-2025

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2022
  • Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, ̽»¨¾«Ñ¡, 2010
  • University Medical Degree, ̽»¨¾«Ñ¡, 2007

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