探花精选

Oscar Wiklander

Oscar Wiklander

Assistant Professor
Visiting address: Alfred Nobels All茅 8, 14152 Huddinge
Postal address: H5 Laboratoriemedicin, H5 BCM Wiklander, 171 77 Stockholm
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About me

  • Dr. Wiklander received his PhD in 2017 at KI shortly after receiving his certificate as a 探花精选 doctor (leg. l盲k) following funding as a MD/PhD-student (forskar-AT). He then continued as a resident in oncology (ST-l盲k) in parallel with conducting his post-doctoral studies until 2023 and 2022, respectively. He divides his time between clinical work and is currently a specialist physician in oncology at Karolinska University Hospital, Theme Cancer, and a team leader with focus on extracellular vesicles in cancer settings, at the department of Laboratory Medicine, KI.

Research

  • Research area/interest: Extracellular vesicle-based precision medicine in cancer. Extracellular vesicles (EVs) are a heterogenous group of lipid-bilayer nanovesicles that are secreted by all cells and can be found in all body fluids. These natural nanovesicles range in size from 30-2, 000 nm in diameter and can impact both neighbouring cells or cells at distance. EVs contain lipids, proteins, and nucleic acid species from the source cell, and have the unique ability to convey these macromolecules via an advanced system of intercellular communication. EVs can be seen as a fingerprint of its source cell, reflecting its status and content, and are thus studied as potential biomarkers of various diseases, with particular focus on cancer. The main focus of Dr. Wiklander's research team is to utilize EVs as 1) therapeutic vehicles for advance cancer therapeutics and 2) investigate tumor-derived EVs as potential liquid biopsies for improved diagnostics in cancer settings.

Articles

  • Article: RSC CHEMICAL BIOLOGY. 2025
    Bestas B; Estupinan HY; Wang Q; Kharazi S; He C; K. Mohammad D; Gupta D; Wiklander OPB; Lehto T; Lundin KE; Berglof A; Karlsson MCI; Abendroth F; El Andaloussi S; Gait MJ; Wood MJA; Leumann CJ; Stetsenko DA; Mansson R; Wengel J; Zain R; Smith CIE
  • Article: JOURNAL OF CONTROLLED RELEASE. 2025;382:113665
    Offens A; Teeuwen L; Akpinar GG; Steiner L; Kooijmans S; Mamand D; Weissinger H; Kall A; Eldh M; Wiklander OPB; El-Andaloussi S; Karlsson MCI; Vader P; Gabrielsson S
  • Article: JOURNAL OF EXTRACELLULAR VESICLES. 2025;14(2):e70042
    Singh B; Fredriksson Sundbom M; Muthukrishnan U; Natarajan B; Stransky S; Gorgens A; Nordin JZ; Wiklander OPB; Sandblad L; Sidoli S; El Andaloussi S; Haney M; Gilthorpe JD
  • Article: NATURE BIOMEDICAL ENGINEERING. 2024;8(11):1453-1468
    Wiklander OPB; Mamand DR; Mohammad DK; Zheng W; Jawad Wiklander R; Sych T; Zickler AM; Liang X; Sharma H; Lavado A; Bost J; Roudi S; Corso G; Lennaard AJ; Abedi-Valugerdi M; Maeger I; Alici E; Sezgin E; Nordin JZ; Gupta D; Goergens A; EL Andaloussi S
  • Article: ADVANCED SCIENCE. 2024;11(42):e2407619
    Zickler AM; Liang X; Gupta D; Mamand DR; De Luca M; Corso G; Errichelli L; Hean J; Sen T; Elsharkasy OM; Kamei N; Niu Z; Zhou G; Zhou H; Roudi S; Wiklander OPB; Gorgens A; Nordin JZ; Castilla-Llorente V; EL Andaloussi S
  • Article: JOURNAL OF PROTEOME RESEARCH. 2024;23(9):4114-4127
    Sharma N; Angori S; Sandberg A; Mermelekas G; Lehtio J; Wiklander OPB; Gorgens A; El Andaloussi S; Eriksson H; Pernemalm M
  • Article: JOURNAL OF EXTRACELLULAR BIOLOGY. 2024;3(9):1-16
    Marchan-脕lvarez JG; Teeuwen L; Mamand D; Gabrielsson S; Blomgren K; Wiklander O; Newton P
  • Article: JOURNAL OF EXTRACELLULAR VESICLES. 2024;13(7):e12471
    Mamand DR; Bazaz S; Mohammad DK; Liang X; Pavlova S; Mim C; Gabrielsson S; Nordin JZ; Wiklander OPB; Abedi-Valugerdi M; EL-Andaloussi S
  • Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2024;129:111584
    Mamand DR; Bazaz S; Mohammad DK; Saher O; Wiklander OPB; Sadeghi B; Hassan M; EL-Andaloussi S; Abedi-Valugerdi M
  • Article: JOURNAL OF EXTRACELLULAR VESICLES. 2024;13(2):e12404
    Welsh JA; Goberdhan DCI; O'Driscoll L; Buzas EI; Blenkiron C; Bussolati B; Cai H; Di Vizio D; Driedonks TAP; Erdbrugger U; Falcon-Perez JM; Fu Q-L; Hill AF; Lenassi M; Lim SK; Mahoney MG; Mohanty S; Moller A; Nieuwland R; Ochiya T; Sahoo S; Torrecilhas AC; Zheng L; Zijlstra A; Abuelreich S; Bagabas R; Bergese P; Bridges EM; Brucale M; Burger D; Carney RP; Cocucci E; Colombo F; Crescitelli R; Hanser E; Harris AL; Haughey NJ; Hendrix A; Ivanov AR; Jovanovic-Talisman T; Kruh-Garcia NA; Faustino VK-L; Kyburz D; Lasser C; Lennon KM; Lotvall J; Maddox AL; Martens-Uzunova ES; Mizenko RR; Newman LA; Ridolfi A; Rohde E; Rojalin T; Rowland A; Saftics A; Sandau US; Saugstad JA; Shekari F; Swift S; Ter-Ovanesyan D; Tosar JP; Useckaite Z; Valle F; Varga Z; van der Pol E; van Herwijnen MJC; Wauben MHM; Wehman AM; Williams S; Zendrini A; Zimmerman AJ; Thery C; Witwer KW
  • Article: NATURE COMMUNICATIONS. 2023;14(1):4734
    Zheng W; Raedler J; Sork H; Niu Z; Roudi S; Bost JPP; Goergens A; Zhao Y; Mamand DRR; Liang X; Wiklander OPB; Lehto T; Gupta D; Nordin JZZ; EL Andaloussi S
  • Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(7):e12248
    Liang X; Niu Z; Galli V; Howe N; Zhao Y; Wiklander OPB; Zheng W; Wiklander RJ; Corso G; Davies C; Hean J; Kyriakopoulou E; Mamand DR; Amin R; Nordin JZ; Gupta D; Andaloussi SEL
  • Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(6):e12238
    Gorgens A; Corso G; Hagey DW; Wiklander RJ; Gustafsson MO; Felldin U; Lee Y; Bostancioglu RB; Sork H; Liang X; Zheng W; Mohammad DK; van DWSI; Vader P; Zickler AM; Mamand DR; Ma L; Holme MN; Stevens MM; Wiklander OPB; El Andaloussi S
  • Article: PHARMACEUTICS. 2021;14(1):38
    Lennaard AJ; Mamand DR; Wiklander RJ; EL Andaloussi S; Wiklander OPB
  • Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098
    Gupta D; Wiklander OPB; G枚rgens A; Concei莽茫o M; Corso G; Liang X; Seow Y; Balusu S; Feldin U; Bostancioglu B; Jawad R; Mamand DR; Lee YXF; Hean J; M盲ger I; Roberts TC; Gustafsson M; Mohammad DK; Sork H; Backlund A; Lundin P; de Fougerolles A; Smith CIE; Wood MJA; Vandenbroucke RE; Nordin JZ; El-Andaloussi S
  • Article: BIOMEDICINES. 2021;9(8):1046
    Bazaz S; Lehto T; Tops R; Gissberg O; Gupta D; Bestas B; Bost J; Wiklander OPB; Sork H; Zaghloul EM; Mamand DR; Hallbrink M; Sillard R; Saher O; Ezzat K; Smith CIE; El Andaloussi S; Lehto T
  • Article: BIOMATERIALS. 2021;266:120435
    Conceica M; Forcina L; Wiklander OPB; Gupta D; Nordin JZ; Vrellaku B; McClorey G; Mager I; Gorgens A; Lundin P; Musaro A; Wood MJA; Andaloussi SEL; Roberts TC
  • Article: ACTA ONCOLOGICA. 2020;59(11):1382-1387
    Kessler LE; Wiklander O; Hamberg E; Bergh J; Foukakis T; Matikas A
  • Article: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 2020;18:880-892
    Berger E; Colosetti P; Jalabert A; Meugnier E; Wiklander OPB; Jouhet J; Errazurig-Cerda E; Chanon S; Gupta D; Rautureau GJP; Geloen A; El-Andaloussi S; Panthu B; Rieusset J; Rome S
  • Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1800222
    Gupta D; Liang X; Pavlova S; Wiklander OPB; Corso G; Zhao Y; Saher O; Bost J; Zickler AM; Piffko A; Maire CL; Ricklefs FL; Gustafsson O; Llorente VC; Gustafsson MO; Bostancioglu RB; Mamand DR; Hagey DW; Goergens A; Nordin JZ; EL Andaloussi S
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All other publications

  • Book chapter: CANCER-TARGETED DRUG DELIVERY: METHODS IN PHARMACOLOGY AND TOXICOLOGY. 2025;p. 125-153
    Ilamathi HS; El Andaloussi S; Wiklander OPB
  • Preprint: BIORXIV. 2024
    Singh B; Sundbom MF; Muthukrishnan U; Natarajan B; Stransky S; G枚rgens A; Nordin J; Wiklander O; Sandblad L; Sidoli S; Andaloussi SEL; Haney M; Gilthorpe J
  • Preprint: RESEARCH SQUARE. 2023
    Liang X; Gupta D; Xie J; Wonterghem E; Hoecke L; Hean J; Niu Z; Wiklander O; Zheng W; Wiklander R; He R; Mammad D; Bost J; Zhou G; Zhou H; Roudi S; Zickler A; Gorgens A; Hagey D; de Jong O; Uy A; Zong Y; Mager I; Perez C; Roberts T; Vader P; Fougerolles A; Wood M; Vandenbroucke R; Nordin J; El-Andaloussi S
  • Preprint: BIORXIV. 2023
    Zheng W; R盲dler J; Sork H; Niu Z; Roudi S; Bost J; G枚rgens A; Zhao Y; Mamand D; Liang X; Wiklander O; Lehto T; Gupta D; Nordin J; EL Andaloussi S
  • Preprint: BIORXIV. 2023
    Liang X; Gupta D; Xie J; Wonterghem EV; Hoecke LV; Hean J; Niu Z; Wiklander O; Zheng W; Wiklander RJ; He R; Mamand D; Bost J; Zhou G; Zhou H; Roudi S; Zickler AM; Gorgens A; Hagey D; de Jong O; Uy AG; Zong Y; Mager I; Perez CM; Roberts T; Vader P; Fougerolles AD; Wood M; Vandenbroucke R; Nordin J; EL Andaloussi S
  • Preprint: BIORXIV. 2023
    Zickler A; Liang X; Gupta D; Mamand D; Luca MD; Corso G; Errichelli L; Hean J; Sen T; Elsharkasy O; Kamei N; Niu Z; Zhou G; Zhou H; Roudi S; Wiklander O; G枚rgens A; Nordin J; Castilla-Llorente V; Andaloussi SEL
  • Other: RESPIRATION. 2023;102(5):402-404
    Jungebluth P; Holzgraefe B; Lim ML; Duru AD; Lundin V; Heldring N; Wiklander OPB; Nordin JZ; Chrobok M; Roderburg C; Sjoqvist S; Anderstam B; Rodriguez AB; C. Haag J; Gustafsson Y; Roddewig KG; Jones P; Wood MJA; Luedde T; Teixeira AI; Hermanson O; Winqvist O; Kalzen H; El Andaloussi S; Alici E; Macchiarini P
  • Review: EXTRACELLULAR VESICLES AND CIRCULATING NUCLEIC ACIDS. 2023;4(2):170-190
    Gupta D; Wiklander OPB; Wood MJA; El-Andaloussi S
  • Conference publication: ANNALS OF ONCOLOGY. 2022;33(7):S950
    Sharma N; Mermelekas G; Lehtio J; Wiklander OPB; Gorgens A; Andaloussi S; Pernemalm M; Eriksson H
  • Conference publication: MOLECULAR THERAPY. 2021;29(4):332-333
    Wiklander OPB; Jawad R; Mamand DR; Sharma H; Liang X; Gupta D; Bost J; Zickler AM; Zheng W; Nordin JZ; Gorgens A; Andaloussi SEL
  • Conference publication: MOLECULAR THERAPY. 2021;29(4):220
    Liang X; Gupta D; Galli V; Zheng W; Davies C; Hean J; Kyriakopoulou E; Yang X; de Andres J; Mamand DR; Amin R; Niu Z; Jawad R; Wiklander O; Zickler A; Gustafsson M; Gorgens A; Nordin JZ; EL Andaloussi S
  • Preprint: BIORXIV. 2020
    Gupta D; Wiklander OPB; G枚rgens A; Concei莽茫o M; Corso G; Liang X; Seow Y; Balsu S; Felldin U; Bostancioglu B; Fiona Lee YX; Hean J; M盲ger I; Roberts T; Gustafsson M; Mohammad D; Sork H; B盲cklund A; Edvard Smith CI; Wood MJA; Vandenbroucke R; Nordin J; Andaloussi SEL
  • Preprint: BIORXIV. 2020
    Concei莽茫o M; Forcina L; Wiklander O; Gupta D; Nordin J; McClorey G; M盲ger I; G枚rgens A; Lundin P; Musar貌 A; Wood M; Andaloussi SEL; Roberts T
  • Review: AUTOIMMUNITY REVIEWS. 2019;18(6):615-620
    Parodis I; Dani L; Notarnicola A; Martenhed G; Fernstrom P; Matikas A; Wiklander OPB
  • Review: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(492):eaav8521
    Wiklander OPB; Brennan MA; Lotval J; Breakefield XO; EL Andaloussi S
  • Doctoral thesis: 2017
    Wiklander O
  • Corrigendum: STEM CELLS TRANSLATIONAL MEDICINE. 2016;5(6):845
    Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Hagglund H; Mattsson M; Lehtio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
  • Conference publication: TRANSPLANTATION. 2016;100(7):S861
    Jorns C; Watanabe M; Kannisto K; Wiklander O; Zemack H; Strom S; Ericzon B-G; Ellis E
  • Conference publication: HUMAN GENE THERAPY. 2012;23(10):A144-A145
    Stenler S; Wiklander O; Tejedor MB; Hallengard D; Wahren B; Rutland MW; Smith CIE; Lundin KE; Blomberg P

Grants

  • The Swedish Cancer Society
    1 January 2024 - 31 December 2026
  • Swedish Research Council
    1 January 2023 - 31 December 2025

Employments

  • Assistant Professor, Department of Laboratory Medicine, 探花精选, 2024-2030

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, 探花精选, 2018
  • University Medical Degree, 探花精选, 2012

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