̽»¨¾«Ñ¡

Sebastian Ols

Sebastian Ols

Postdoctoral Researcher
Visiting address: BioClinicum J7:20, 17176 Stockholm
Postal address: K2 Medicin, Solna, K2 Infekt Broliden K, 171 77 Stockholm
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About me

  • Sebastian is currently a Postdoctoral Fellow in the King Lab at the Institute
    for Protein Design, University of Washington, Seattle and affiliated to
    ̽»¨¾«Ñ¡.
    I completed my doctoral studies in the research group of Professor Karin
    Loré studying how B cell responses are modulated by nanoparticle vaccine
    formulations. In particular, I studied how the breadth and potency of
    anti-viral antibody and B cell responses is affected by antigen display. My
    thesis was titled: "Cellular and molecular mechanisms for induction of broad
    anti-viral B cell responses through vaccination [1]."
    2023 Sven Gard Prize for Best Thesis in Virology at ̽»¨¾«Ñ¡ in
    2022 [2]
    2017-2022 PhD in Medical Science, ̽»¨¾«Ñ¡, Stockholm, Sweden.
    2014-2016 Master of Science in Medical Biotechnology, KTH Royal Institute of
    Technology, Stockholm, Sweden.
    2010-2014 Bachelor of Science in Biotechnology, KTH Royal Institute of
    Technology, Stockholm, Sweden.
    [1] ;amp;pk_vid=9c47331a68b2c4c71678442012ba3098
    [2]

Research

  • A better understanding of how the immune system interacts with vaccines will
    allow us to rationally select formulations that have the capacity to elicit
    stronger immunity and can be advanced into clinical testing. Our studies can
    ultimately provide information on vaccine antigen persistence, distribution,
    and the immunological steps for the onset of B cell responses to understand
    the generation of high-quality and durable antibody responses.

Articles

  • Article: NATURE. 2025;638(8050):553-561
    Dowling QM; Park Y-J; Fries CN; Gerstenmaier NC; Ols S; Yang EC; Wargacki AJ; Dosey A; Hsia Y; Ravichandran R; Walkey CD; Burrell AL; Veesler D; Baker D; King NP
  • Article: JCI INSIGHT. 2024;9(9):e175401
    Hellgren F; Rosdahl A; Cerveira RA; Lenart K; Ols S; Gwon Y-D; Kurt S; Delis AM; Joas G; Evander M; Normark J; Ahlm C; Forsell MNE; Cajander S; Lore K
  • Article: NPJ VACCINES. 2024;9(1):17
    Lenart K; Cerveira RA; Hellgren F; Ols S; Sheward DJ; Kim C; Cagigi A; Gagne M; Davis B; Germosen D; Roy V; Alter G; Letscher H; Van Wassenhove J; Gros W; Gallouet A-S; Le Grand R; Kleanthous H; Guebre-Xabier M; Murrell B; Patel N; Glenn G; Smith G; Lore K
  • Article: IMMUNITY. 2023;56(10):2425-2441.e14
    Ols S; Lenart K; Cerveira RA; Miranda MC; Brunette N; Kochmann J; Corcoran M; Skotheim R; Philomin A; Cagigi A; Fiala B; Wrenn S; Marcandalli J; Hellgren F; Thompson EA; Lin A; Gegenfurtner F; Kumar A; Chen M; Phad GE; Graham BS; Perez L; Borst AJ; Hedestam GBK; Ruckwardt TJ; King NP; Lore K
  • Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(7):189
    Yan X; Ols S; Arcoverde Cerveira R; Lenart K; Hellgren F; Ye K; Cagigi A; Buggert M; Nimmerjahn F; Hojen JF; Parera D; Pessara U; Fischer S; Lore K
  • Article: NATURE COMMUNICATIONS. 2023;14(1):3713
    Hellgren F; Cagigi A; Cerveira RA; Ols S; Kern T; Lin A; Eriksson B; Dodds MG; Jasny E; Schwendt K; Freuling C; Mueller T; Corcoran M; Hedestam GBK; Petsch B; Lore K
  • Article: NATURE COMMUNICATIONS. 2023;14(1):2164
    Yu M; Charles A; Cagigi A; Christ W; osterberg B; Falck-Jones S; Azizmohammadi L; ahlberg E; Falck-Jones R; Svensson J; Nie M; Warnqvist A; Hellgren F; Lenart K; Arcoverde Cerveira R; Ols S; Lindgren G; Lin A; Maecker H; Bell M; Johansson N; Albert J; Sundling C; Czarnewski P; Klingstroem J; Faernert A; Lore K; Smed-Soerensen A
  • Article: MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 2022;27:309-323
    Lenart K; Hellgren F; Ols S; Yan X; Cagigi A; Cerveira RA; Winge I; Hanczak J; Mueller SO; Jasny E; Schwendt K; Rauch S; Petsch B; Lore K
  • Article: JCI INSIGHT. 2021;6(22):e151463
    Cagigi A; Yu M; Osterberg B; Svensson J; Falck-Jones S; Vangeti S; Ahlberg E; Azizmohammadi L; Warnqvist A; Falck-Jones R; Gubisch PC; Odemis M; Ghafoor F; Eisele M; Lenart K; Bell M; Johansson N; Albert J; Salde J; Pettie DD; Murphy MP; Carter L; King NP; Ols S; Normark J; Ahlm C; Forsell MN; Farnert A; Lore K; Smed-Sorensen A
  • Article: IMMUNITY. 2021;54(9):2005-2023.e10
    Glaros V; Rauschmeier R; Artemov AV; Reinhardt A; Ols S; Emmanouilidi A; Gustafsson C; You Y; Mirabello C; Bjorklund AK; Perez L; King NP; Mansson R; Angeletti D; Lore K; Adameyko I; Busslinger M; Kreslavsky T
  • Article: JOURNAL OF IMMUNOLOGY. 2021;207(4):1033-1043
    Sandberg JT; Ols S; Lofling M; Varnait R; Lindgren G; Nilsson O; Rombo L; Kale M; Lore K; Blom K; Ljunggren H-G; Lindgren G; Nilsson O; Rombo L; Kale M
  • Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2020;481:112792
    Silva MH; Lepzien R; Ols S; Dahlberg B; Grunewald J; Lore K; Smed-Sorensen A; Correia-Neves M; Empadinhas N; Farnert A; Kallenius G; Sundling C
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(5):2332-2346
    Lin A; Apostolovic D; Jahnmatz M; Liang F; Ols S; Tecleab T; Wu C; van Hage M; Solovay K; Rubin K; Locht C; Thorstensson R; Thalen M; Lore K
  • Article: CELL REPORTS. 2020;30(12):3964-3971.e7
    Ols S; Yang L; Thompson EA; Pushparaj P; Tran K; Liang F; Lin A; Eriksson B; Hedestam GBK; Wyatt RT; Lore K
  • Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2019;472:16-24
    Lindgren G; Ols S; Thompson EA; Lore K
  • Article: CELL. 2019;176(6):1420-1431.e17
    Marcandalli J; Fiala B; Ols S; Perotti M; de van der Schueren W; Snijder J; Hodge E; Benhaim M; Ravichandran R; Carter L; Sheffler W; Brunner L; Lawrenz M; Dubois P; Lanzavecchia A; Sallusto F; Lee KK; Veesler D; Correnti CE; Stewart LJ; Baker D; Lore K; Perez L; King NP
  • Article: JCI INSIGHT. 2018;3(10):120692
    Thompson EA; Ols S; Miura K; Rausch K; Narum DL; Spangberg M; Juraska M; Wille-Reece U; Weiner A; Howard RF; Long CA; Duffy PE; Johnston L; O'neil CP; Lore K
  • Article: JOURNAL OF IMMUNOLOGY. 2018;200(1):286-294
    Lin A; Liang F; Thompson EA; Vono M; Ols S; Lindgren G; Hassett K; Salter H; Ciaramella G; Lore K
  • Article: MOLECULAR THERAPY. 2017;25(12):2635-2647
    Liang F; Lindgren G; Lin A; Thompson EA; Ols S; Rohss J; John S; Hassett K; Yuzhakov O; Bahl K; Brito LA; Salter H; Ciaramella G; Lore K
  • Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1539
    Lindgren G; Ols S; Liang F; Thompson EA; Lin A; Hellgren F; Bahl K; John S; Yuzhakov O; Hassett KJ; Brito LA; Salter H; Ciaramella G; Lore K

All other publications

  • Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):4080
    Hellgren F; Cagigi A; Cerveira RA; Ols S; Kern T; Lin A; Eriksson B; Dodds MG; Jasny E; Schwendt K; Freuling C; Mueller T; Corcoran M; Hedestam GKB; Petsch B; Lore K; Usa C
  • Doctoral thesis: 2022
    Ols S
  • Review: JOURNAL OF INTERNAL MEDICINE. 2022;291(1):32-50
    Castro Dopico X; Ols S; Lore K; Karlsson Hedestam GB
  • Editorial comment: NATURE BIOMEDICAL ENGINEERING. 2019;3(5):331-332
    Ols S; Lore K
  • Corrigendum: FRONTIERS IN IMMUNOLOGY. 2019;10:614
    Lindgren G; Ols S; Liang F; Thompson EA; Lin A; Hellgren F; Bahl K; John S; Yuzhakov O; Hassett KJ; Brito LA; Salter H; Ciaramella G; Lore K

Employments

  • Postdoctoral Researcher, Department of Medicine, ̽»¨¾«Ñ¡, 2023-2025

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Medicine, Solna, ̽»¨¾«Ñ¡, 2022

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