Susanne L枚ffler
Affiliated to Research
E-mail: susanne.loffler@ki.se
Visiting address: Biomedicum, Solnav盲gen 9, 17165 Solna
Postal address: C4 Neurovetenskap, C4 AIMES, 171 77 Stockholm
Part of:
About me
- I joined Agneta Richter-Dahlfors' group with the Swedish Medical Nanoscience
center as a postdoctoral fellow in 2012. Here, I'm working to find solutions
for problems in today's healthcare and 探花精选 sector. Working here gives me
the chance to apply my interdisciplinary background from Life Sciences,
Neuroscience, and Bio探花精选 Engineering. I like learning new things everyday
and seeing ideas progress from a thought to a sketch on a paper towel towards
a scientific proof-of concept study to a device, that is actually helping
people in real-life.
PhD: 鈥漈owards closed-loop Deep Brain Stimulation 鈥 An integratedApproach
for Neural Recording and Microstimulation鈥 [1]
Department for Signal Processing, Faculty of Computer Science and
Engineering, University of Lu虉beck, Germany
BSc: Molecular Biotechnology, University of Lu虉beck, Germany (Thesis:
鈥滺igh frequency electrical stimulation in the caudate nucleus in vivo:
Quantification of the neurotransmitters GABA and glutamate鈥
MSc: Molecular Life Sciences, University of Lu虉beck, Germany (Thesis:
鈥滳haracterization of the HFS induced GABA release in the corpus
striatum of the rat in vivo鈥
[1]
Research
- Organic electronics are a group of materials that combine the versability and
flexibility of polymers with electronic conductivity. With the help of these
conducting polymers, it becomes possible to built electronic devices from
materials that have the same look and feel as the plastics, which we are
using in our everyday life.
Really interesting is the fact that these materials can change their physical
properties depending on how we adres them electronically. That means, we can
actively transform one material into another by applying an electrical
potential.
I'm investigating the use of these materials in Life Science and Medical
applications as active surfaces for cell attachment, as delivery devices for
neuroactive substances or as sensors for bacterial infection.
* Active Surfaces for cell Attachment/Release: We're using different redox
states of the polymers to prevent attachment or release cells
* Artificial Synapse: We're using an organic electronic ion pump, which
releases neurotransmitters with high spatiotemporal control and pair it
with an entity for real-time neurotransmitter detection
* Epithelial Integrity Sensing: We're using an organic electronic sensor,
which has a large active surface area due to the porosity of the polymer
to detect the paracellular diffusion at an epithelial cell layer.
Articles
- Article: CHEMBIOCHEM. 2022;23(11):e202100684
- Article: NPJ BIOFILMS AND MICROBIOMES. 2020;6(1):35
- Article: SENSORS AND ACTUATORS B-CHEMICAL. 2019;297:126703
- Article: JOURNAL OF CONTROLLED RELEASE. 2016;243:283-290
- Article: JOURNAL OF MATERIALS CHEMISTRY B. 2015;3(25):4997-5000
- Article: PHYSICS IN MEDICINE AND BIOLOGY. 2013;58(3):555-568
- Article: FRONTIERS IN NEUROENGINEERING. 2013;6:6
- Article: NEUROPHARMACOLOGY. 2012;63(5):898-904
- Article: BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK. 2012;57:858-861
- Article: BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK. 2012;57:104-107
- Article: ADVANCED MATERIALS. 2011;23(38):4403-4408
- Article: JOURNAL OF NEUROSCIENCE METHODS. 2007;159(2):286-290
All other publications
- Corrigendum: NPJ BIOFILMS AND MICROBIOMES. 2021;7(1):4
- Review: FRONTIERS IN CHEMISTRY. 2019;7:265
- Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2017;282(1):24-36
- Review: JOURNAL OF MATERIALS CHEMISTRY B. 2015;3(25):4979-4992
- Review: ELECTRONICS. 2015;4(4):879-908