Sven-Christian Pawelzik
Adjunct Lecturer
E-mail: sven-christian.pawelzik@ki.se
Visiting address: BioClinicum, Plan 8,Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K2 Medicin, Solna, K2 Kardiov m Bäck M, 171 77 Stockholm
About me
- I am a team leader in the Translational Cardiology group at the Department of
Medicine, Solna (MedS), driven to learn about new aspects of human health and
apply this knowledge to contribute to innovative therapeutic approaches. My
focus of interest is inflammation as basis of cardiovascular diseases.
2011 - 2016 Postdoctoral Researcher, University of Pennsylvania, Philadelphia, PA, USA
2010 PhD in Medical Science, ̽»¨¾«Ñ¡, Sweden
2006 MSc, Human Biology, University of Marburg, Germany
2001 BSc, Human Biology, University of Marburg, Germany
Teaching
Main supervisor for two PhD students
Co-supervisor for two PhD students
Main supervisor for several BSc and MSc students (Biomedicine, Biochemistry,
Molecular Biology)PhD course: Lipid Metabolism and Inflammation in Cardiovascular Disease ()
PhD course: Bioactive Lipid Mediators in Human Disease, University of Modena and Reggio Emilia, 2025
Articles
- Article: ESC HEART FAILURE. 2025;12(2):1469-1473Qin Z; Baeck M; Franco-Cereceda A; Pawelzik S-C
- Journal article: EUROPEAN HEART JOURNAL OPEN. 2023;4(1):oeae008Back M; Banach M; Braunschweig F; De Rosa S; Flachskampf FA; Kahan T; Ketelhuth DFJ; Lancellotti P; Larsson SC; Mellbin L; Nagy E; Savarese G; Szummer K; Wahl D
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(6):5392Sundqvist MOO; Warme J; Hofmann R; Pawelzik S-C; Back M
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2023;194:308-315Pawelzik S-C; Arnardottir H; Sarajlic P; Mahdi A; Vigor C; Zurita J; Zhou B; Kolmert J; Galano J-M; Religa D; Durand T; Wheelock CE; Back M
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2022;179(19):4709-4721Carracedo M; Pawelzik S-C; Artiach G; Pouwer MG; Plunde O; Saliba-Gustafsson P; Ehrenborg E; Eriksson P; Pieterman E; Stenke L; Princen HMG; Franco-Cereceda A; Back M
- Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2022;12(9):e895Arnardottir H; Pawelzik S-C; Sarajlic P; Quaranta A; Kolmert J; Religa D; Wheelock CE; Back M
- Article: BIOCHEMICAL PHARMACOLOGY. 2022;201:115075Bardin M; Pawelzik S-C; Lagrange J; Mahdi A; Arnardottir H; Feve B; Regnault V; Lacolley P; Michel J-B; Mercier N; Back M
- Journal article: CARDIOLOGY PLUS. 2022;7(1):3-11Bäck M; Hashem M; Giani A; Pawelzik S-C; Franco-Cereceda A
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(24):e142883Arnardottir H; Thul S; Pawelzik S-C; Karadimou G; Artiach G; Gallina AL; Mysdotter V; Carracedo M; Tarnawski L; Caravaca AS; Baumgartner R; Ketelhuth DF; Olofsson PS; Paulsson-Berne G; Hansson GK; Back M
- Article: CIRCULATION. 2021;144(20):1629-1645Franco Cereceda A; Bäck M; Plunde O; Pawelzik S-C
- Journal article: CIRCULATION. 2021;144(20):1629-1645Sainz-Jaspeado M; Smith RO; Plunde O; Pawelzik S-C; Jin Y; Nordling S; Ding Y; Aspenstrom P; Hedlund M; Bastianello G; Ascione F; Li Q; Demir CS; Fernando D; Daniel G; Franco-Cereceda A; Kroon J; Foiani M; Petrova TV; Kilimann MW; Back M; Claesson-Welsh L
- Article: AMERICAN HEART JOURNAL. 2021;231:105-109Waerme J; Sundqvist M; Mars K; Aladellie L; Pawelzik S-C; Erlinge D; Jernberg T; James S; Hofmann R; Baeck M
- Article: CELLS. 2020;9(7):E1710-1710Karadimou G; Plunde O; Pawelzik S-C; Carracedo M; Eriksson P; Franco-Cereceda A; Paulsson-Berne G; Back M
- Article: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020;2020:5197376-9Mercier N; Pawelzik S-C; Pirault J; Carracedo M; Persson O; Wollensack B; Franco-Cereceda A; Back M
- Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2019;145:106361Pawelzik S-C; Avignon A; Idborg H; Boegner C; Stanke-Labesque F; Jakobsson P-J; Sultan A; Back M
- Article: BRITISH JOURNAL OF PHARMACOLOGY. 2019;176(24):4625-4638Larsson K; Steinmetz J; Bergqvist F; Arefin S; Spahiu L; Wannberg J; Pawelzik S-C; Morgenstern R; Stenberg P; Kublickiene K; Korotkova M; Jakobsson P-J
- Article: JOURNAL OF IMMUNOLOGY. 2018;200(12):4004-4011Ocana JA; Romer E; Sahu R; Pawelzik S-C; FitzGerald GA; Kaplan MH; Travers JB
- Article: CIRCULATION. 2016;134(4):328-338Tang SY; Monslow J; Grant GR; Todd L; Pawelzik S-C; Chen L; Lawson J; Pure E; FitzGerald GA
- Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2014;91(6):269-275Idborg H; Pawelzik S-C; Perez-Manso M; Bjork L; Hamrin J; Herlenius E; Jakobsson P-J
- Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2013;102:1-12Leclerc P; Pawelzik S-C; Idborg H; Spahiu L; Larsson C; Stenberg P; Korotkova M; Jakobsson P-J
- Article: BIOCHEMISTRY. 2011;50(35):7684-7693Prage EB; Pawelzik S-C; Busenlehner LS; Kim K; Morgenstern R; Jakobsson P-J; Armstrong RN
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(38):29254-29261Pawelzik S-C; Uda NR; Spahiu L; Jegerschold C; Stenberg P; Hebert H; Morgenstern R; Jakobsson P-J
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1801(4):462-472Hoffmann M; Lopez JJ; Pergola C; Feisst C; Pawelczik S; Jakobsson P-J; Sorg BL; Glaubitz C; Steinhilber D; Werz O
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(44):18757-18762Hanaka H; Pawelzik S-C; Johnsen JI; Rakonjac M; Terawaki K; Rasmuson A; Sveinbjornsson B; Schumacher MC; Hamberg M; Samuelsson B; Jakobsson P-J; Kogner P; Radmark O
- Article: LEUKEMIA & LYMPHOMA. 2009;50(7):1198-1203Johansson A-S; Pawelzik S-C; Larefalk A; Jakobsson P-J; Holmberg D; Lindskog M
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(32):11110-11115Jegerschold C; Paweizik S-C; Purhonen P; Bhakat P; Gheorghe KR; Gyobu N; Mitsuoka K; Morgenstern R; Jakobsson P-J; Hebert H
- Article: CIRCULATION. 2008;117(13):1701-1710Degousee N; Fazel S; Angoulvant D; Stefanski E; Pawelzik S-C; Korotkova M; Arab S; Liu P; Lindsay TF; Zhuo S; Butany J; Li R-K; Audoly L; Schmidt R; Angioni C; Geisslinger G; Jakobsson P-J; Rubin BB
- Journal article: GBM ANNUAL SPRING MEETING MOSBACH 2006. 2006;2006(Spring)Pawelzik S-C; Jegerschöld C; Pettersson PL; Morgenstern R; Hebert H; Jakobsson P-J
- Journal article: VALUE IN HEALTH. 2004;7(2):144-152Dodel RC; Haacke C; Zamzow K; Pawelzik S; Spottke A; Rethfeldt M; Siebert U; Oertel WH; Schöffski O; Back T
- Show more
All other publications
- Review: METABOLITES. 2022;12(8):721Idborg H; Pawelzik S-C
- Editorial comment: CARDIOVASCULAR RESEARCH. 2022;118(2):353-354Pawelzik S-C; Back M
- Preprint: MEDRXIV. 2021Arnardottir H; Pawelzik S-C; Sarajlic P; Quaranta A; Kolmert J; Religa D; Wheelock C; Bäck M
- Conference publication: ATHEROSCLEROSIS. 2021;331:E9Arnardottir H; Thul S; Karadimou G; Pawelzik S-C; Artiach G; Mysdotter V; Carracedo M; Tarnawski L; Caravaca AS; Baumgartner R; Ketelhuth DF; Olofsson PS; Paulsson-Berne G; Hansson GK; Back M
- Review: FRONTIERS IN PHYSIOLOGY. 2021;11:624657Arnardottir H; Pawelzik S-C; ohlund Wistbacka U; Artiach G; Hofmann R; Reinholdsson I; Braunschweig F; Tornvall P; Religa D; Back M
- Review: TOXINS. 2020;12(4):E227-227Ebert T; Pawelzik S-C; Witasp A; Arefin S; Hobson S; Kublickiene K; Shiels PG; Back M; Stenvinkel P
- Editorial comment: ANNALS OF TRANSLATIONAL MEDICINE. 2020;8(6):258Pawelzik S-C; Back M
- Doctoral thesis: 2010Pawelzik S-C
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2010;71(6):508Leclerc P; Larsson C; Spahiu L; Pawelzik S-C; Idborg H; Stenberg P; Korotkova M; Jakobsson P-J
- Conference publication: ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2009;65:S77Hebert H; Jegerschoeld C; Purhonen P; Bhakat P; Gheorghe K; Gyobu N; Mitsuoka K; Pawelzik S; Jakobsson P-J; Morgenstern R
Grants
- VINNOVA21 November 2022 - 31 December 2025Purpose and goal: This project aims to introduce personalized medicine for an optimized omega-3 fatty acid treatment in cardiovascular prevention. More specifically, the goal is to develop a personalized medicine CVD prevention decision tool to determine if omega-3 treatment is likely to be beneficial in individual patients, and determine what PUFA, dose, and formulation to use for an optimized response towards cardiovascular health. Expected results and effects: The anticipated outcome of the project is the digital decision support system (DSS) OmegaPerMed Prevention Tool that can identify responders and non-responders to omega-3 treatment. This could hence be the first personalized medicine tool to be widely implemented in international CVD treatment guidelines for secondary prevention to the benefit of large patient population in Europe and world-wide. In addition, it has the potential to be expanded towards personalized dietary PUFA recommendations for primary CVD prevention and other non-CVD associated with chronic inflammation. Approach and implementation: This multidisciplinary project will explore well characterized cohorts and clinical trials for interactions between genes, polyunsaturated fatty acid (PUFA) exposure, cardiovascular disease risk and lipidomic markers towards beneficial effects of omega-3 PUFA. Complimentary lipidomic methods will be employed for mapping PUFA, PUFA sources, and PUFA-derived mediators as biomarkers. All available data will be integrated using artificial intelligence to develop the OmegaPerMed Prevention Tool, which will be continuously tested in a feasibility trial.
- European Commission1 November 2022CArdiovascular REsolution of INflammation to promote HEALTH (CARE-IN-HEALTH), responds to an unmet ̽»¨¾«Ñ¡ need by addressing one of the critical hallmarks of the phenotypic and functional cardiovascular during the transition from health to Cardiovascular disease (CVD) : Chronic Inflammation.  Identifying the resolution of the chronic lipid-driven/-regulated vascular inflammation allows to develop and test, in a real-life setting, tools for use in health care and by citizens to stay healthy.
- Swedish Research Council1 January 2013 - 31 December 2015
Employments
- Adjunct Lecturer, Department of Medicine, ̽»¨¾«Ñ¡, 2023-2027
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Medicine, Solna, ̽»¨¾«Ñ¡, 2010