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Juni Palmgren

Juni Palmgren

Professor Emeritus/Emerita
E-postadress: juni.palmgren@ki.se
Telefon: +46852486120
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: Nobels väg 12a, 17165 Stockholm
Postadress: C8 Medicinsk epidemiologi och biostatistik, C8 MEB III, 171 77 Stockholm
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Om mig

  • Min forskning i statistisk metodik omfattar utvecking av teorin för generaliserade linjära modeller och överlevnadsanalys till att hantera flerdimensionella utfallsvariabler och ofullständiga data. Detta leder oundvikligen till komplexa skattningsprocedurer, inkluderande likelihoodbaserade EM strategier och Bayesiansk simuleringsbaserad inferens. Användningen av "kausalmodeller" för att hantera effekten av icke-slumpmässigt bortfall i randomiserade studier har under flere Ã¥r varit ett av mina intresseomrÃ¥den. En utveckling av denna kausalmodellram till longitudinella data och observationsstudier är angeläget. Ett tidigare intresseomrÃ¥de, som under senare tid fÃ¥tt ny aktualitet, är utvecklingen av teorin för generaliserade linjära modeller till en klass av modeller där varje observationsenhet har sin egen specifika icke-linjära link funktion. Som komplement till ovanstÃ¥ende delar jag intresset för modern statistisk genetik med flere av mina biostatistikkolleger inom och utom landet.

    Hur utnyttjar man modern statistisk metodik för studier i genetisk epidemiologi och molekylärgenetik? Aktuella frågor rör studieupplägg och analys vid "Linkage disequilibrium mapping" och "associationsstudier" för fall-kontroll data och för familjebaserade data, inklusive tvillingdata. Hantering av selektiva sampling strategier och av longitudinella multivariata fenotyper ingår i problemställningen. Det mesta av min tillämpade forskning relaterar till cancer och även till psykiatriska och metabola sjukdomar.

    Utbildning:
    • 1973 Fil Mag (Matematik), Helsingfors Universitet, Finland
    • 1987 Pol Dr (Statistik), Helsingfors Universitet, Finland
    • 1989 Docent (Statistik), Helsingfors Universitet, Finland

Artiklar

  • Article: JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION. 2017;24(5):950-957
    Spjuth O; Karlsson A; Clements M; Humphreys K; Ivansson E; Dowling J; Eklund M; Jauhiainen A; Czene K; Gronberg H; Sparen P; Wiklund F; Cheddad A; Palsdottir P; Rantalainen M; Abrahamsson L; Laure E; Litton J-E; Palmgren J
  • Article: CLINICAL CANCER RESEARCH. 2017;23(10):2584-2592
    Li J; Ivansson E; Klevebring D; Tobin NP; Lindstrom LS; Holm J; Prochazka G; Cristando C; Palmgren J; Tornberg S; Humphreys K; Hartman J; Frisell J; Rantalainen M; Lindberg J; Hall P; Bergh J; Gronberg H; Czene K
  • Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2016;24(4):521-528
    Spjuth O; Krestyaninova M; Hastings J; Shen H-Y; Heikkinen J; Waldenberger M; Langhammer A; Ladenvall C; Esko T; Persson M-A; Heggland J; Dietrich J; Ose S; Gieger C; Ried JS; Peters A; Fortier I; de Geus EJC; Klovins J; Zaharenko L; Willemsen G; Hottenga J-J; Litton J-E; Karvanen J; Boomsma DI; Groop L; Rung J; Palmgren J; Pedersen NL; McCarthy MI; van Duijn CM; Hveem K; Metspalu A; Ripatti S; Prokopenko I; Harris JR
  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2015;107(10):djv185
    Sundstrom K; Ploner A; Arnheim-Dahlstrom L; Eloranta S; Palmgren J; Adami H-O; Helm NY; Sparen P; Dillner J
  • Article: MOLECULAR THERAPY. 2015;23(2):321-329
    Kanerva A; Koski A; Liikanen I; Oksanen M; Joensuu T; Hemminki O; Palmgren J; Hemminki K; Hemminki A
  • Article: NEW ENGLAND JOURNAL OF MEDICINE. 2014;370(10):932-942
    Bill-Axelson A; Holmberg L; Garmo H; Rider JR; Taari K; Busch C; Nordling S; Haggman M; Andersson S-O; Spangberg A; Andren O; Palmgren J; Steineck G; Adami H-O; Johansson J-E
  • Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2013;22(1):150-158
    Sundstrom K; Ploner A; Dahlstrom LA; Palmgren J; Dillner J; Adami H-O; Ylitalo N; Sparen P
  • Journal article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. MONOGRAPHS. 2012;2012(45):230-233
    Holmberg L; Bill-Axelson A; Steineck G; Garmo H; Palmgren J; Johansson E; Adami H-O; Johansson J-E
  • Article: EUROPEAN UROLOGY. 2012;62(2):204-209
    Vickers A; Bennette C; Steineck G; Adami H-O; Johansson J-E; Bill-Axelson A; Palmgren J; Garmo H; Holmberg L
  • Article: PROSTATE. 2012;72(1):30-39
    Szulkin R; Holmberg E; Stattin P; Xu J; Zheng S; Palmgren J; Gronberg H; Wiklund F
  • Article: PLOS ONE. 2011;6(8):e22547
    Humphreys K; Grankvist A; Leu M; Hall P; Liu J; Ripatti S; Rehnstroem K; Groop L; Klareskog L; Ding B; Gronberg H; Xu J; Pedersen NL; Lichtenstein P; Mattingsdal M; Andreassen OA; O'Dushlaine C; Purcell SM; Sklar P; Sullivan PF; Hultman CM; Palmgren J; Magnusson PKE
  • Article: NEW ENGLAND JOURNAL OF MEDICINE. 2011;364(18):1708-1717
    Bill-Axelson A; Holmberg L; Ruutu M; Garmo H; Stark JR; Busch C; Nordling S; Haggman M; Andersson S-O; Bratell S; Spangberg A; Palmgren J; Steineck G; Adami H-O; Johansson J-E
  • Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2011;26(1):67-77
    Almqvist C; Adami H-O; Franks PW; Groop L; Ingelsson E; Kere J; Lissner L; Litton J-E; Maeurer M; Michaëlsson K; Palmgren J; Pershagen G; Ploner A; Sullivan PF; Tybring G; Pedersen NL
  • Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(12):1322-1326
    Leu M; Humphreys K; Surakka I; Rehnberg E; Muilu J; Rosenstrom P; Almgren P; Jaaskelainen J; Lifton RP; Kyvik KO; Kaprio J; Pedersen NL; Palotie A; Hall P; Gronberg H; Groop L; Peltonen L; Palmgren J; Ripatti S
  • Article: INTERNATIONAL JOURNAL OF CANCER. 2010;127(8):1923-1930
    Dahlstrom LA; Ylitalo N; Sundstrom K; Palmgren J; Ploner A; Eloranta S; Sanjeevi CB; Andersson S; Rohan T; Dillner J; Adami H-O; Sparen P
  • Article: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 2010;19(10):2469-2478
    Sundstrom K; Eloranta S; Sparen P; Dahlstrom LA; Gunnell A; Lindgren A; Palmgren J; Ploner A; Sanjeevi CB; Melbye M; Dillner J; Adami H-O; Ylitalo N
  • Article: STATISTICS IN MEDICINE. 2010;29(2):275-283
    Wienke A; Ripatti S; Palmgren J; Yashin A
  • Article: BIOMETRICS. 2009;65(2):514-520
    Sjolander A; Humphreys K; Vansteelandt S; Bellocco R; Palmgren J
  • Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2009;17(4):533-536
    Ripatti S; Becker T; Bickeboeller H; Dominicus A; Fischer C; Humphreys K; Jonasdottir G; Moreau Y; Olsson M; Ploner A; Sheehan N; Van Steen K; Baur M; van Duijn C; Palmgren J
  • Article: STATISTICS IN MEDICINE. 2008;27(27):5786-5798
    Dominicus A; Ripatti S; Pedersen NL; Palmgren J
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Alla övriga publikationer

  • Editorial comment: NATURE GENETICS. 2019;51(6):924-930
    Njolstad PR; Andreassen OA; Brunak S; Borglum AD; Dillner J; Esko T; Franks PW; Freimer N; Groop L; Heimer H; Hougaard DM; Hovig E; Hveem K; Jalanko A; Kaprio J; Knudsen GP; Melbye M; Metspalu A; Mortensen PB; Palmgren J; Palotie A; Reed W; Stefansson H; Stitziel NO; Sullivan PF; Thorsteinsdottir U; Vaudel M; Vuorio E; Werge T; Stoltenberg C; Stefansson K
  • Conference publication: CANCER RESEARCH. 2017;77:p2-03-03-p2-03-03
    Czene K; Ivansson E; Klevebring D; Tobin NP; Lindstrom LS; Holm J; Prochazka G; Hilliges C; Palmgren J; Tornberg S; Humphreys K; Hartman J; Frisell J; Rantalainen M; Lindberg J; Hall P; Bergh J; Gronberg H; Li J
  • Conference publication: GENETIC EPIDEMIOLOGY. 2015;39(7):533
    Benner C; Pirinen M; Salomaa V; Palmgren J; Ripatti S
  • Book chapter: WILEY STATSREF: STATISTICS REFERENCE ONLINE. 2014;p.
    Kuha J; Skinner C; Palmgren J
  • Book chapter: WILEY STATSREF: STATISTICS REFERENCE ONLINE. 2014;p.
    Palmgren J
  • Book chapter: LECTURE NOTES IN COMPUTER SCIENCE. 2014;p. 32-40
    Data Integration between Swedish National Clinical Health Registries and Biobanks Using an Availability System
    Spjuth O; Heikkinen J; Litton J-E; Palmgren J; Krestyaninova M
  • Conference publication: GENETIC EPIDEMIOLOGY. 2007;31(6):631
    Humphreys K; Jonasdottir G; Palmgren J
  • Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2007;14:22
    Smestad C; Brynedal B; Jonasdottir G; Lorentzen AR; Masterman T; Akesson E; Spurkland A; Lie BA; Palmgren J; Celius EG; Hillert J; Harbo HF
  • Published conference paper: BMC GENETICS. 2005;6(Suppl 1):S92
    Jonasdottir G; Palmgren J; Humphreys K
  • Book chapter: ENCYCLOPEDIA OF STATISTICAL SCIENCES. 2005;p.
    Palmgren J
  • Book chapter: ENCYCLOPEDIA OF BIOSTATISTICS. 2005;p.
    Kuha J; Skinner C; Palmgren J
  • Book chapter: ENCYCLOPEDIA OF BIOSTATISTICS. 2005;p.
    Palmgren J
  • Book chapter: ENCYCLOPEDIA OF STATISTICAL SCIENCES. 2004;p.
    Palmgren J
  • Editorial comment: SCANDINAVIAN JOURNAL OF STATISTICS. 2004;31(2):159-160
    Palmgren J
  • Book chapter: ADVANCES IN CLINICAL TRIAL BIOSTATISTICS: CHAPMAN & HALL/CRC BIOSTATISTICS SERIES. 2003;p.
    Goetghebeur E; Palmgren J
  • Letter: ULTRASOUND IN OBSTETRICS & GYNECOLOGY. 2002;20(1):102-103
    Kieler H; Cnattingius S; Haglund B; Palmgren J; Axelsson O
  • Letter: EPIDEMIOLOGY. 2002;13(3):370
    Kieler H; Cnattingius S; Palmgren J; Haglund B; Axelsson O
  • Review: STATISTICAL METHODS IN MEDICAL RESEARCH. 2000;9(1):57-72
    Palmgren J
  • Book chapter: GENERALIZED LINEAR MODELS: LECTURE NOTES IN STATISTICS. 1985;p. 128-136
    Palmgren J; Ekholm A
  • Book chapter: GLIM 82: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON GENERALISED LINEAR MODELS: LECTURE NOTES IN STATISTICS. 1982;p. 128-143
    Ekholm A; Palmgren J

Forskningsbidrag

  • Optimization of Cervical Cancer Prevention - New challenges with HPV vaccination and primary HPV screening.
    Swedish Cancer Society
    1 January 2017
    Preventive screening against cervical cancer has greatly reduced the incidence of the disease in Sweden and many other high-income countries. The test used so far is soon replaced by one that identifies human papillomavirus (HPV), which causes cervical cancer. For almost 10 years, vaccines have been available in Sweden that protect against the most serious forms of HPV. It is mainly women aged 10-18 who have been vaccinated and these will enter the screening program in a few years. The new screening program needs to be optimized both for those who are HPV-vaccinated and for those who are not. The aim of the research project is to investigate how this process is affected by the conventional cytological screening, the new screening for finding HPV and by HPV vaccination, by means of a quantitative dynamic simulation model for the cervical cancer development process. We intend to evaluate and optimize screening for cervical cancer for women who are HPV-vaccinated and women who are not HPV-vaccinated by:    • Examine at what age the screening should start • Calculate optimal screening intervals for women of different ages We will be able to predict, plan and evaluate the costs and benefits of various strategies to prevent cervical cancer and recommend how to coordinate HPV vaccination and screening in order to prevent as much disease and death in cervical cancer as possible. The results will be in support of healthcare professionals and community planners and individual women will almost immediately benefit from improvements in the cervical cancer screening program.
  • Optimization of Cervical Cancer Prevention - New challenges with HPV vaccination and primary HPV screening.
    Swedish Cancer Society
    1 January 2016
    Preventive screening against cervical cancer has greatly reduced the incidence of the disease in Sweden and many other high-income countries. The test used so far is soon replaced by one that identifies human papillomavirus (HPV), which causes cervical cancer. For almost 10 years, vaccines have been available in Sweden that protect against the most serious forms of HPV. It is mainly women aged 10-18 who have been vaccinated and these will enter the screening program in a few years. The new screening program needs to be optimized both for those who are HPV-vaccinated and for those who are not. The aim of the research project is to investigate how this process is affected by the conventional cytological screening, the new screening for finding HPV and by HPV vaccination, by means of a quantitative dynamic simulation model for the cervical cancer development process. We intend to evaluate and optimize screening for cervical cancer for women who are HPV-vaccinated and women who are not HPV-vaccinated by:   • Examine at what age the screening should start • Calculate optimal screening intervals for women of different ages We will be able to predict, plan and evaluate the costs and benefits of various strategies to prevent cervical cancer and recommend how to coordinate HPV vaccination and screening in order to prevent as much disease and death in cervical cancer as possible. The results will be in support of healthcare professionals and community planners and individual women will almost immediately benefit from improvements in the cervical cancer screening program.
  • Repatriation Juni Palmgren
    Swedish Research Council
    1 January 2016 - 31 December 2018
  • Optimization of Cervical Cancer Prevention - New challenges with HPV vaccination and primary HPV screening.
    Swedish Cancer Society
    1 January 2015
    Preventive screening against cervical cancer has greatly reduced the incidence of the disease in Sweden and many other high-income countries. The test used so far is soon replaced by one that identifies human papillomavirus (HPV), which causes cervical cancer. For almost 10 years, vaccines have been available in Sweden that protect against the most serious forms of HPV. It is mainly women aged 10-18 who have been vaccinated and these will enter the screening program in a few years. The new screening program needs to be optimized both for those who are HPV-vaccinated and for those who are not. The aim of the research project is to investigate how this process is affected by the conventional cytological screening, the new screening for finding HPV and by HPV vaccination, by means of a quantitative dynamic simulation model for the cervical cancer development process. We intend to evaluate and optimize screening for cervical cancer for women who are HPV-vaccinated and women who are not HPV-vaccinated by:    • Examine at what age the screening should start • Calculate optimal screening intervals for women of different ages We will be able to predict, plan and evaluate the costs and benefits of various strategies to prevent cervical cancer and recommend how to coordinate HPV vaccination and screening in order to prevent as much disease and death in cervical cancer as possible. The results will be in support of healthcare professionals and community planners and individual women will almost immediately benefit from improvements in the cervical cancer screening program.
  • Swedish Research Council
    1 January 2011 - 31 January 2011
  • Basresurser till huvudsekreterare för forskningens infrastrukturer (Juni Palmgren).
    Swedish Research Council
    1 December 2010 - 30 June 2015
  • Base resources for the chief secretary of research infrastructures (June Palmgren).
    Swedish Research Council
    1 December 2010 - 30 June 2015
  • Swedish Research Council
    1 January 2010 - 31 December 2012
  • Swedish Research Council
    1 January 2009 - 31 December 2009
  • Swedish Research Council
    1 January 2009 - 31 December 2009
  • Swedish Research Council
    1 January 2009 - 31 December 2011
  • Swedish Research Council
    1 January 2008 - 31 December 2008
  • Fogarty International Center
    19 June 1989 - 31 December 1989

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