̽»¨¾«Ñ¡

Antonio Gigliotti Rothfuchs

Antonio Gigliotti Rothfuchs

Principal Researcher | Docent
Telephone: +46852485252
Visiting address: Solnavägen 9, C9, 17165 Solna
Postal address: C1 Mikrobiologi, tumör- och cellbiologi, C1 Parasitology and CF Rothfuchs, 171 77 Stockholm

About me

  • My laboratory works on tuberculosis. 


    I have more than 15 years of research experience with intracellular
    pathogens, primarily Mycobacterium species, under Biosafety Level 2 (BSL2)
    and BSL3, and in mouse models. I am Chairman of the Biosafety Committee at
    ̽»¨¾«Ñ¡ and help oversee KI's regulations on biosafety,
    containment work in different biosafety levels and the handling of
    genetically-modified microorganisms. I am also Director of the BSL3 core
    facility at Biomedicum which supports research on risk group 3 bacteria,
    parasites and viruses.

    Associate Professor of Immunology (Docent), ̽»¨¾«Ñ¡. 2014
    Doctor of Medical Science (PhD) in Immunobiology, ̽»¨¾«Ñ¡. 2004
    Master of Medical Science with a Major in Biomedicine, ̽»¨¾«Ñ¡. 1999

Research

  • My laboratory does basic research on the immunology and infection biology of
    mycobacteria. We are particularly interested in the aerobiology of
    Mycobacterium tuberculosis and in techniques to capture and analyze
    pathogens in the air. We have developed an aerobiology platform in BSL3 where
    highly-pathogenic microorganisms can be safely and experimentally
    aerosolized, collected using different air samplers and detected by different
    analytical methods. We are using this platform to investigate the performance
    of an electrostatic air sampler for M. tuberculosis developed in the lab;
    to investigate biosafety and sampling performance of commercial samplers; and
    to study the effects of aerosol transport on the survival, infectivity and
    immune response of M. tuberculosis and SARS-CoV-2.

Teaching

  • Coordinator, KI Summer School in Medical Research (KISS)
    Teacher, Basic Laboratory Safety (course 2690)
    Teacher, Immunology and Microbiology (course 1BI041)

Articles

  • Article: INFECTIOUS DISEASES. 2024;56(11):991-999
    de Sousa NR; Margerie L; Steponaviciute L; Roux J; Kinahan MW; Olsson D; Asgeirsson H; Udekwu KI; Rothfuchs AG
  • Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(3):e13342
    Krmeska V; Shen L; Nylen S; Wowk PF; Rothfuchs AG
  • Article: MOLECULAR PSYCHIATRY. 2022;27(10):3939-3950
    Samudyata; Oliveira AO; Malwade S; de Sousa NR; Goparaju SK; Gracias J; Orhan F; Steponaviciute L; Schalling M; Sheridan SD; Perlis RH; Rothfuchs AG; Sellgren CM
  • Article: JOURNAL OF IMMUNOLOGY. 2022;208(11):2549-2557
    Krmeska V; Aggio JB; Nylen S; Wowk PF; Rothfuchs AG
  • Article: INDOOR AIR. 2022;32(3):e13023
    de Sousa NR; Steponaviciute L; Margerie L; Nissen K; Kjellin M; Reinius B; Salaneck E; Udekwu KI; Rothfuchs AG
  • Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267
    Classon CH; Li M; Clavero AL; Ma J; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs AG; Eidsmo L; Coquet JM; Nylen S
  • Article: JOURNAL OF IMMUNOLOGY. 2021;206(4):776-784
    Aggio JB; Krmeska V; Ferguson BJ; Wowk PF; Rothfuchs AG
  • Article: ANNALS OF WORK EXPOSURES AND HEALTH. 2020;64(8):852-865
    de Sousa NR; Shen L; Silcott D; Call CJ; Rothfuchs AG
  • Article: NATURE COMMUNICATIONS. 2020;11(1):4812
    Smyrlaki I; Ekman M; Lentini A; de Sousa NR; Papanicolaou N; Vondracek M; Aarum J; Safari H; Muradrasoli S; Rothfuchs AG; Albert J; Hoegberg B; Reinius B
  • Article: TUBERCULOSIS. 2020;120:101896
    de Sousa NR; Sandstrom N; Shen L; Hakansson K; Vezozzo R; Udekwu KI; Croda J; Rothfuchs AG
  • Article: PLOS PATHOGENS. 2018;14(5):e1007008
    Feng X; Classon C; Teran G; Yang Y; Li L; Chan S; Ribacke U; Rothfuchs AG; Coquet JM; Nylen S
  • Article: SCIENTIFIC REPORTS. 2017;7:43989
    Nasi A; Bollampalli VP; Sun M; Chen Y; Amu S; Nylen S; Eidsmo L; Rothfuchs AG; Rethi B
  • Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2016;(116):54620
    Bollampalli VP; Nylen S; Rothfuchs AG
  • Article: JOURNAL OF IMMUNOLOGY. 2016;196(5):2262-2271
    Obieglo K; Feng X; Bollampalli VP; Dellacasa-Lindberg I; Classon C; Oesterblad M; Helmby H; Hewitson JP; Maizels RM; Rothfuchs AG; Nylen S
  • Article: PLOS PATHOGENS. 2015;11(10):e1005206
    Bollampalli VP; Yamashiro LH; Feng X; Bierschenk D; Gao Y; Blom H; Henriques-Normark B; Nylen S; Rothfuchs AG
  • Article: MICROBES AND INFECTION. 2015;17(5):337-344
    Carvalho NB; Oliveira FS; Marinho FAV; de Almeida LA; Fahel JS; Bafica A; Rothfuchs AG; Zamboni DS; Caliari MV; Oliveira SC
  • Article: JOURNAL OF IMMUNOLOGY. 2012;188(2):649-660
    Roffe E; Rothfuchs AG; Santiago HC; Marino APMP; Ribeiro-Gomes FL; Eckhaus M; Antonelli LRV; Murphy PM
  • Article: PLOS ONE. 2012;7(11):e47835
    Rothfuchs AG; Roffe E; Gibson A; Cheever AW; Ezekowitz RAB; Takahashi K; Steindel M; Sher A; Bafica A
  • Article: IMMUNITY. 2011;34(5):807-819
    Egen JG; Rothfuchs AG; Feng CG; Horwitz MA; Sher A; Germain RN
  • Article: MICROBES AND INFECTION. 2011;13(2):198-201
    Marakalala MJ; Guler R; Matika L; Murray G; Jacobs M; Brombacher F; Rothfuchs AG; Sher A; Brown GD
  • Article: EXPERIMENTAL PARASITOLOGY. 2010;125(4):315-324
    Min-Oo G; Ayi K; Bongfen SE; Tam M; Radovanovic I; Gauthier S; Santiago H; Rothfuchs AG; Roffe E; Sher A; Mullick A; Fortin A; Stevenson MM; Kain KC; Gros P
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2010;120(5):1674-1682
    Antonelli LRV; Rothfuchs AG; Goncalves R; Roffe E; Cheever AW; Bafica A; Salazar AM; Feng CG; Sher A
  • Article: JOURNAL OF IMMUNOLOGY. 2009;182(11):6915-6925
    Rothfuchs AG; Egen JG; Feng CG; Antonelli LRV; Bafica A; Winter N; Locksley RM; Sher A
  • Article: BLOOD. 2008;112(4):1461-1471
    Soehnlein O; Zernecke A; Eriksson EE; Rothfuchs AG; Pham CT; Herwald H; Bidzhekov K; Rottenberg ME; Weber C; Lindbom L
  • Article: EUROPEAN RESPIRATORY JOURNAL. 2008;32(2):405-412
    Soehnlein O; Oehmcke S; Ma X; Rothfuchs AG; Frithiof R; van Rooijen N; Morgelin M; Herwald H; Lindbom L
  • Article: IMMUNITY. 2008;28(2):271-284
    Egen JG; Rothfuchs AG; Feng CG; Winter N; Sher A; Germain RN
  • Article: JOURNAL OF IMMUNOLOGY. 2007;179(6):3463-3471
    Rothfuchs AG; Bafica A; Feng CG; Egen JG; Williams DL; Brown GD; Sher A
  • Article: JOURNAL OF IMMUNOLOGY. 2006;177(10):7086-7093
    Feng CG; Kaviratne M; Rothfuchs AG; Cheever A; Hieny S; Young HA; Wynn TA; Sher A
  • Article: JOURNAL OF IMMUNOLOGY. 2006;176(11):6982-6990
    Rothfuchs AG; Trumstedt C; Mattei F; Schiavoni G; Hidmark A; Wigzell H; Rottenberg ME
  • Article: JOURNAL OF IMMUNOLOGY. 2004;172(10):6345-6353
    Rothfuchs AG; Trumstedt C; Wigzell H; Rottenberg ME
  • Article: JOURNAL OF IMMUNOLOGY. 2004;172(4):2407-2415
    Rothfuchs AG; Kreuger MR; Wigzell H; Rottenberg ME
  • Article: INFECTION AND IMMUNITY. 2003;71(7):4102-4111
    Eriksson E; Dons L; Rothfuchs AG; Heldin P; Wigzell H; Rottenberg ME
  • Article: JOURNAL OF IMMUNOLOGY. 2001;167(11):6453-6461
    Rothfuchs AG; Gigliotti D; Palmblad K; Andersson U; Wigzell H; Rottenberg ME
  • Article: INFECTION AND IMMUNITY. 2001;69(7):4232-4241
    Kullberg MC; Rothfuchs AG; Jankovic D; Caspar P; Wynn TA; Gorelick PL; Cheever AW; Sher A
  • Article: JOURNAL OF IMMUNOLOGY. 2000;164(9):4812-4818
    Rottenberg ME; Rothfuchs AG; Gigliotti D; Ceausu M; Une C; Levitsky V; Wigzell H
  • Article: JOURNAL OF IMMUNOLOGY. 1999;162(5):2829-2836
    Rottenberg ME; Rothfuchs ACG; Gigliotti D; Svanholm C; Bandholtz L; Wigzell H
  • Show more

All other publications

  • Letter: INDOOR AIR. 2022;32(11):e13169
    Rufino de Sousa N; Steponaviciute L; Margerie L; Nissen K; Kjellin M; Reinius B; Salaneck E; Udekwu KI; Rothfuchs AG
  • Corrigendum: INDOOR AIR. 2022;32(8):e13085
    Rufino de Sousa N; Steponaviciute L; Margerie L; Nissen K; Kjellin M; Reinius B; Salaneck E; Udekwu KI; Rothfuchs AG
  • Doctoral thesis: 2004
    Rothfuchs ACGT
  • Review: CURRENT OPINION IN IMMUNOLOGY. 2002;14(4):444-451
    Rottenberg ME; Gigliotti-Rothfuchs A; Wigzell H

Grants

  • BSL3 Biomedicum-SciLifeLab collaborative platform
    SciLifeLab
  • Advancing environmental virus profiling and risk assessment for public health perspective
    KAW/SciLifeLab
  • Kapacitetsuppbyggnad av BSL3 för att utveckla COVID-19 forskning pÃ¥ aktivt virus samt celler och vävnader infekterade med SARS-CoV-2
    TetraLaval/TetraPak
  • Survival and infectiousness of Mycobacterium tuberculosis in aerosols
    ̽»¨¾«Ñ¡
  • Diagnosing and tracing tuberculosis through electrostatic cough sampling
    Swedish Heart-Lung Foundation
  • Testing BSL3 Biomedicum capabilities and more
    SciLifeLab
  • Aerosolization of Mycobacterium tuberculosis: establishing its role in the transmission of tuberculosis
    Swedish Research Council
  • BSL3 Biomedicum Core Facility
    ̽»¨¾«Ñ¡
  • Exploring how aerosol transport and particle size impacts mycobacterial infection
    ̽»¨¾«Ñ¡
  • EnBiFlu, testing the efficiency of multifaceted enviornmental assessment of avian influenza threats and outbreaks
    SciLifeLab
  • BSL3 capacity for Pandemic Laboratory Preparedness
    SciLifeLab
  • Swedish Environmental Epidemiology Center, a holistic pandemic preparedness capability for health-related environmental research and surveillance
    SciLifeLab

Employments

  • Principal Researcher, Department of Microbiology, Tumor and Cell Biology, ̽»¨¾«Ñ¡, 2022-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2014
  • Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, ̽»¨¾«Ñ¡, 2004
  • Master Of Medical Science, ̽»¨¾«Ñ¡, 1999

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