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Experimental Orthopedics – Josefine Naili Team

The research aims to increase knowledge about the functional and biomechanical consequences of joint injuries, joint diseases, and skeletal deformities in children and adults.

Central to the research are various methods for evaluating joint mobility, joint and foot loading, and their connection to perceived pain and biomarkers in blood. Furthermore, we aim to investigate their significance for disease progression, treatment selection, and outcomes of administered treatments.

graphic picture with process description
BIOFUNC project Foto: Figure created with biorender.com

BIOFUNC â€“ Studies focusing on osteoarthritis development and the link between knee function and blood biomarkers.

In individuals with established knee osteoarthritis, we have found associations between substances in the blood and the progression of knee function and pain over time. An anterior cruciate ligament (ACL) rupture is a common knee injury among athletes, and nearly half will develop knee osteoarthritis later in life. Surgical ACL reconstruction has not been shown to reduce the risk of osteoarthritis, and currently, there is no way to predict who will develop knee osteoarthritis.

The ongoing BIOFUNC project evaluates knee function, perceived symptoms, and blood substances in individuals with established osteoarthritis and those who have undergone ACL reconstruction, who thereby have an increased risk of developing osteoarthritis. The goal is to identify methods to predict osteoarthritis development.

illustration of the projekt process
Recurrent foot deformity in children with clubfoot Photo: Figure created with biorender.com

Recurrent foot deformity in children with clubfoot
The project aims to evaluate standardized follow-up for children with clubfoot (congenital talipes equinovarus) to identify the best methods for detecting recurrence (return of foot deformity). The methods include examining ankle range of motion, dynamic foot loading during walking (pedobarography), clinical assessment tools, and video observation of children walking. Can we predict the risk of recurrence in children with clubfoot?

Publications

All publications from group members

  • Article: OSTEOARTHRITIS AND CARTILAGE OPEN. 2025;7(1):100543
    Naili JE; Ahmed AS; Hedstrom M; Simonsen MB; Brostrom EW; Harris HE; Vegvari A; Aulin C
  • Article: BMC RHEUMATOLOGY. 2025;9(1):32
    Gijon-Nogueron G; Balint P; Batalov A; Ostojic P; Sollmann N; van Middelkoop M; Agricola R; Naili JE; Milovanovic D; Popova S; Kazakova M; Nuernberger S; Aulin C; Karalilova R; Henrotin Y
  • Article: JOURNAL OF ARTHROPLASTY. 2024;39(11):2708-2713
    Heijbel S; W-Dahl A; E-Naili J; Hedstrom M
  • Journal article: GAIT & POSTURE. 2024;113:60-61
    Naili JE; Simonsen MB; Aulin C
  • Article: GAIT & POSTURE. 2024;113:224-231
    Bartonek A; Naili JE; Simonsen MB; Eriksson M
  • Article: BMC MUSCULOSKELETAL DISORDERS. 2024;25(1):560
    Naili JE; Astrom E; Lowing J; Reimeringer M; Lowing K
  • Article: BMC MUSCULOSKELETAL DISORDERS. 2024;25(1):425
    Naili JE; Lindeberg M; Esbjoernsson A-C
  • Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:s479-s480
    Naili J; Hedstrom M; Ahmed AS; Simonsen MB; Brostrom EW; Harris H; Vegvari A; Aulin C
  • Journal article: GAIT & POSTURE. 2023;106:s54-s55
    Eriksson M; Naili JE; Simonsen MB; Bartonek Ã…
  • Journal article: GAIT & POSTURE. 2023;106:s53-s54
    Naili JE; Hedström M; Ahmed A; Simonsen MB; Broström EW; Harris HE; Vegvari A; Aulin C
  • Article: SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH. 2023;15(3):357-360
    Naili JE; Markstroem JL; Haeger CK
  • Article: GAIT & POSTURE. 2023;100:96-102
    Naili JE; Brekke AF; Simonsen MB; Hirata RP; Overgaard S; Holsgaard-Larsen A
  • Article: SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH. 2023;15(1):45-51
    Markstrom JL; Naili JE; Hager CK
  • Article: AMERICAN JOURNAL OF SPORTS MEDICINE. 2022;50(14):3856-3865
    Aufwerber S; Silbernagel KG; Ackermann PW; Naili JE
  • Journal article: GAIT & POSTURE. 2022;97:s352-s353
    Naili JE; Åström E; Löwing K
  • Article: JOURNAL OF ORTHOPAEDIC RESEARCH. 2022;40(8):1932-1942
    Aufwerber S; Naili JE; Silbernagel KG; Ackermann PW
  • Article: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY. 2022;142(8):1985-1994
    Naili JE; Stalman A; Valentin A; Skorpil M; Weidenhielm L
  • Article: JOURNAL OF ORTHOPAEDIC RESEARCH. 2022;40(5):1182-1193
    Biggs P; Holsgaard-Larsen A; Holt CA; Naili JE
  • Article: BMC MUSCULOSKELETAL DISORDERS. 2022;23(1):397
    Brostrom EW; Antonissen L; von Heideken J; Esbjornsson A-C; Hagenas L; Naili JE
  • Article: PATIENT PREFERENCE AND ADHERENCE. 2022;16:2203-2211
    Aronsson L; Frithiof A; Rostedal A; Rudberg C; Ekstrom W
  • Journal article: GAIT & POSTURE. 2021;90:19-20
    Brekke AF; Naili JE; Simonsen MB; Hirata RP; Holsgaard-Larsen A
  • Journal article: GAIT & POSTURE. 2021;90:52-53
    Naili JE; Brekke AF; Simonsen MB; Hirata RP; Larsen AH
  • Journal article: GAIT & POSTURE. 2021;90:40-41
    De Vecchis M; Naili JE; Holsgaard-Larsen A; Broström EW; Wilson C; Whatling GM; Holt CA
  • Article: JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH. 2020;15(1):151
    Esbjornsson A-C; Naili JE
  • Article: ACTA ORTHOPAEDICA. 2020;91(1):88-93
    Heijbel S; Naili JE; Hedin A; W-Dahl A; Nilsson KG; Hedstrom M
  • Article: GAIT & POSTURE. 2019;74:20-26
    Naili JE; Brostrom EW; Clausen B; Holsgaard-Larsen A
  • Article: BMC MUSCULOSKELETAL DISORDERS. 2019;20(1):365
    Nyvang JS; Naili JE; Iversen MD; Brostrom EW; Hedstrom M
  • Conference publication: OSTEOARTHRITIS AND CARTILAGE. 2019;27:S121-S122
    Biggs PR; Holt CA; Naili JE
  • Article: JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY. 2019;20(1):14
    Naili JE; Hedstrom M; Brostrom EW
  • Journal article: GAIT & POSTURE. 2018;65:174-175
    Naili JE; Broström EW; Roos EM; Clausen B; Holsgaard-Larsen A
  • Article: GAIT & POSTURE. 2018;62:140-145
    Naili JE; Brostrom EW; Gutierrez-Farewik EM; Schwartz MH
  • Meeting abstract: OSTEOARTHRITIS AND CARTILAGE. 2018;26:S461-S462
    Naili JE; Gutierrez-Farewik E; Stalman A; Valentin A; Skorpil M; Weidenhielm L
  • Article: KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY. 2017;25(11):3378-3386
    Naili JE; Iversen MD; Esbjornsson A-C; Hedstrom M; Schwartz MH; Hager CK; Brostrom EW
  • Doctoral thesis: 2017
    Naili J
  • Journal article: GAIT & POSTURE. 2017;57:301-302
    Mastrigt NV; Naili JE; Broström EW; Harlaar J; Iversen MD
  • Article: KNEE. 2017;24(3):536-546
    Naili JE; Esbjornsson A-C; Iversen MD; Schwartz MH; Hedstrom M; Hager CI; Brostrom EW
  • Conference publication: OSTEOARTHRITIS AND CARTILAGE. 2017;25:S125-S126
    Naili JE; Brostrom EW; Gutierrez-Farewik EM; Schwartz MH
  • Article: BMC MUSCULOSKELETAL DISORDERS. 2017;18(1):122
    Naili JE; Wretenberg P; Lindgren V; Iversen MD; Hedstrom M; Brostrom EW
  • Conference publication: OSTEOARTHRITIS AND CARTILAGE. 2016;24:S111
    Naili JE; Iversen MD; Esbjornsson A-C; Hedstrom M; Schwartz MH; Hager CK; Brostrom EW
  • Journal article: GAIT & POSTURE. 2015;42:s32
    Naili JE; Esbjörnsson AC; Iversen MD; Schwartz MH; Häger C; Broström EW
  • Journal article: GAIT & POSTURE. 2015;42:s21-s22
    Naili JE; Esbjörnsson A-C; Iversen MD; Hedström M; Schwartz MH; Häger C; Broström EW
  • Journal article: GAIT & POSTURE. 2013;38:s6-s7
    Naili JE; Gutierrez-Farewik EM; Reimeringer M; Esbjörnsson A-C; Broström EW
  • Journal article: GAIT & POSTURE. 2012;36:s53-s54
    Naili J; Esbjörnsson A; Rozumalski A; Schwartz M; Reimeringer M; Broström E
  • Show more
Content reviewer:
20-06-2025