Advancing Regenerative Medicine at KI
Two infrastructure projects have been selected to receive support from StratRegen, aimed at strengthening Stem Cell and Regenerative Medicine research across KI鈥檚 campuses.
At Campus Solna, a new research facility will be established to utilize the spiny mouse (Acomys), a mammal known for its remarkable ability to regenerate tissues. This platform will enable fundamental research into the biological mechanisms that drive tissue regeneration.
Complementing this, at Campus Flemingsberg, funding will enable the development of a dedicated pre-GMP room within the existing Karolinska ATMP Center. This new facility will focus on the automated and scalable culture of adherent cell therapy products, playing a vital role in translating laboratory discoveries into clinical therapies.
By supporting both foundational science and clinical applications, StratRegen is reinforcing KI鈥檚 capacity to drive innovation and excellence in regenerative medicine.
Establishing an Acomys research facility at KI: a novel mammalian platform for regenerative medicine
The African spiny mouse (Acomys species) is an emerging mammalian model that bridges a critical gap in regenerative medicine research, combining mammalian physiology with exceptional regenerative capabilities.
With the StratRegen support we aim to stablish a dedicated Acomys research colony at KI, creating an open platform to serve multiple research groups across KI's regenerative medicine community. This facility will enable broad research into the mechanisms that drive tissue regeneration and repair, with the goal of positioning KI as a leader in this emerging field.
Contact
Enric Llorens Bobadilla
Assistant Professor
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Establishing a pre-GMP facility for automated and scalable culture of adherent cell therapy products at the Karolinska ATMP Center
The promise of cell and gene therapy (CGT) lies in their potential to revolutionize the treatment of a wide range of diseases, including those that are currently incurable. Karolinska ATMP Center takes the advantage of the collective strength of KI and K, and has a clear vision to accelerate translational research into clinical application. With the addition of a pre-GMP room for work with adherent cells, through the grant from Stem Cells and Regenerative Medicine, we can offer a broader spectre of applications within cell and gene therapy. Adhesion cells, which include many types of primary cells and cell lines, often better mimic the in vivo environment compared to suspension cells, and more closely resembles the body's natural conditions.