̽»¨¾«Ñ¡

Publikationer

Utvalda publikationer

• Article: ACS NANO. 2025;19(20):19057-19079

  Malina T; Kaur J; Martin S; Gallud A; Katayama S; Gazzi A; Orecchioni M; Petr M; Srejber M; Haag L; Hamawandi B; Toprak MS; Kere J; Delogu LG; Fadeel B
• Article: NANO TODAY. 2024;54:102084

  Gazzi A; Fusco L; Orecchioni M; Keshavan S; Shin Y; Grivel J-C; Rinchai D; Ahmed EI; Elhanani O; Furesi G; Rauner M; Keren L; Ley K; Casiraghi C; Bedognetti D; Fadeel B; Delogu LG
• Article: MATTER. 2024;7(1):191-215

  Malina T; Hamawandi B; Toprak MS; Chen L; Bjork J; Zhou J; Rosen J; Fadeel B
• Article: ACS NANO. 2023;17(17):17451-17467

  Gupta G; Kaur J; Bhattacharya K; Chambers BJ; Gazzi A; Furesi G; Rauner M; Fuoco C; Orecchioni M; Delogu LG; Haag L; Stehr JE; Thomen A; Bordes R; Malmberg P; Seisenbaeva GA; Kessler VG; Persson M; Fadeel B
• Article: NATURE NANOTECHNOLOGY. 2023;18(1):42-48

  Peng G; Sinkko HM; Alenius H; Lozano N; Kostarelos K; Brautigam L; Fadeel B
• Article: NATURE COMMUNICATIONS. 2022;13(1):3798

  Fortino V; Kinaret PAS; Fratello M; Serra A; Saarimaki LA; Gallud A; Gupta G; Vales G; Correia M; Rasool O; Ytterberg J; Monopoli M; Skoog T; Ritchie P; Moya S; Vazquez-Campos S; Handy R; Grafstrom R; Tran L; Zubarev R; Lahesmaa R; Dawson K; Loeschner K; Larsen EH; Krombach F; Norppa H; Kere J; Savolainen K; Alenius H; Fadeel B; Greco D
• Article: NATURE NANOTECHNOLOGY. 2018;13(7):537-543

  Fadeel B; Farcal L; Hardy B; Vazquez-Campos S; Hristozov D; Marcomini A; Lynch I; Valsami-Jones E; Alenius H; Savolainen K
• Article: CHEM. 2018;4(2):334-358

  Mukherjee SP; Lazzaretto B; Hultenby K; Newman L; Rodrigues AF; Lozano N; Kostarelos K; Malmberg P; Fadeel B
• Article: SCIENCE SIGNALING. 2015;8(395):ra95

  Balasubramanian K; Maeda A; Lee JS; Mohammadyani D; Dar HH; Jiang JF; Croix CMS; Watkins S; Tyurin VA; Tyurina YY; Kloeditz K; Polimova A; Kapralova VI; Xiong Z; Ray P; Klein-Seetharaman J; Mallampalli RK; Bayir H; Fadeel B; Kagan VE
• Article: NATURE NANOTECHNOLOGY. 2010;5(5):354-359

  Kagan VE; Konduru NV; Feng W; Allen BL; Conroy J; Volkov Y; Vlasova II; Belikova NA; Yanamala N; Kapralov A; Tyurina YY; Shi J; Kisin ER; Murray AR; Franks J; Stolz D; Gou P; Klein-Seetharaman J; Fadeel B; Star A; Shvedova AA

Finansiering

Forskningsbidrag

• European Commission

  1 December 2024 - 30 November 2028
• European Commission

  1 March 2023 - 28 February 2027
• Swedish Research Council

  1 January 2022 - 31 December 2025

  Two-dimensional (2D) materials beyond graphene have attracted considerable interest due to their unique physicochemical properties. The overall aim of the current proposal is to expand our knowledge regarding the biological interactions of 2D materials, i.e., transition metal dichalcogenides (TMDs) and transition metal carbides, carbonitrides, and nitrides (collectively known as MXenes). We will place particular emphasis on inflammation, the process by which our body protects us from harm, and we will address interactions with lung cells, as inhalation is an important route of exposure to foreign materials. This proposal builds on previous research on graphene-based materials, and the goal is to pave the way for safe and sustainable handling and use of 2D materials. The specific aims of this project are: (i) to profile the interactions of 2D materials with peripheral blood mononuclear cells with respect to cytocompatibility and cytokine responses using advanced single-cell analysis

  (ii) to study the effects of 2D materials on primary human macrophages and lung cells, and the putative biotransformation of 2D materials in these cells

  (iii) to investigate the biological impact of 2D materials at the molecular level using genome-wide transcriptomics approaches coupled with mass spectrometry-based proteomics

  (iv) to explore the biological interactions of 2D materials in vivo using zebrafish embryos to model inflammation.
• MISTRA - Stiftelsen för miljöstrategisk forskning

  1 January 2014 - 30 September 2023
• European Commission

  1 October 2013 - 30 September 2023

Medarbetare och kontakt

Enhetschef

• 

  Bengt Fadeel

  Professor

  Telefon +46852487737

  E-postadress bengt.fadeel@ki.se

Alla medarbetare i gruppen

• 

  Bengt Fadeel

  Professor

  Telefon +46852487737

  E-postadress bengt.fadeel@ki.se
• 

  Vivek Gohel

  Postdoktor

  E-postadress vivek.gohel@ki.se
• 

  Jasreen Kaur

  Postdoktor

  E-postadress jasreen.kaur@ki.se
• 

  Pragati More

  Postdoktor

  E-postadress pragati.more@ki.se

µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ

̽»¨¾«Ñ¡, Institute of Environmental Medicine, Nobels väg 13, Stockholm, 171 77, Sweden

Postadress

̽»¨¾«Ñ¡, Institute of Environmental Medicine, Nobels väg 13, Stockholm, 171 77, Sweden