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Genetic and epigenetic factors in asthma and allergy – Cilla Söderhäll's research group

Our main aim is to develop molecular diagnostic and prognostic tools for clinical use, that could discriminate between preschool wheezers that will develop chronic asthma and those that will grow out of their symptoms. Today, asthma cannot be efficiently predicted or prevented, and the current treatment in preschool children is not optimal and sometimes even without effect.

Part of the:

Recurrent episodes of wheeze in infants are troublesome for those affected, and a common cause of visits to the emergency room and hospitalization in this age-group. Some of these children (about 30%) will develop asthma, while many will be symptom-free before starting school. Wheeze in young children can vary considerably in terms of severity, duration, risk of relapse, contributing causes, treatability and risk for future chronic asthma. Symptoms may be caused by viral infections, allergen exposure or airway irritants.

We aim to develop molecular tools that can be used for both diagnos