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Around 50 000 patients are treated in Intensive Care Units and more than 800 000 patients undergo surgery and anesthesia in Sweden every year. With perioperative and intensive care offered to an elder and comorbid population complications increase, contributing to long-term morbidity. In the perioperative setting complications increase risk of death five-fold. Perioperative death, within 30 days following surgery, has been reported to be the 3rd leading cause of mortality, exceeded only by heart disease and cancer.

We have multiple ongoing projects regarding long-term mortality and morbidity after perioperative care; focusing on myocardial injury and -infarction, acute kidney injury as well as cognitive dysfunction and stroke. We are investigating intraoperative hypotension and other modifiable factors. For future interventional trials to be effective it is essential to focus on the right patients, those with the highest risk of adverse events; can we describe these at-risk-individuals? What are the perioperative risks of stroke, pneumonia and acute kidney injury? We also study potential effects of wireless monitoring of high-risk patients in the postoperative and post intensive care setting.

With regards to critical illness and multiorgan failure, we investigate the impact of acute kidney injury (AKI) and study both kidney injury biomarkers- and functional biomarkers and their association with long-term outcomes. Is it possible to detect patients at risk for further renal deterioration and can interventional programs minimize that risk?  

Selected publications

Hergens M P, Bell M, Haglund P, Sundström J, Lampa E, Nederby-Öhd J, Rotzén Östlund M, Cars T.
Eur J Epidemiol. 2022 Jan 27

Hallqvist L, Granath F, Fored M, Bell M
Anesth Analg 2021 Feb;():

Renberg M, Jonmarker O, Kilhamn N, Rimes-Stigare C, Bell M, Hertzberg D
Ultrasound J 2021 Feb;13(1):3

Kane-Gill SL, Meersch M, Bell M
Curr Opin Crit Care 2020 12;26(6):556-562

Faxén UL, Hallqvist L, Benson L, Schrage B, Lund LH, Bell M
J Card Fail 2020 Dec;26(12):1034-1042

Renberg M, Kilhamn N, Lund K, Hertzberg D, Rimes-Stigare C, Bell M
Ultrasound J 2020 May;12(1):28

Hallqvist L, Granath F, Bell M
Br J Anaesth 2020 07;125(1):47-54

Zettersten E, Jäderling G, Larsson E, Bell M
Sci Rep 2019 10;9(1):14222

Bell M, Eriksson LI, Svensson T, Hallqvist L, Granath F, Reilly J, Myles PS
EClinicalMedicine ;11():18-26

Rimes-Stigare C, Ravn B, Awad A, Torlén K, Martling CR, Bottai M, Mårtensson J, Bell M
Crit Care Res Pract 2018 ;2018():7698090

Hallqvist L, Granath F, Huldt E, Bell M
Eur J Anaesthesiol 2018 04;35(4):273-279

Ravn B, Prowle JR, MÃ¥rtensson J, Martling CR, Bell M
Crit Care Med 2017 Sep;45(9):e932-e940

• Innovationsfonden, SLL
   
• Stockholm County Council
   
• ±áÂáä°ù³Ù-³¢³Ü²Ô²µ-´Ú´Ç²Ô»å±ð²Ô
   
• Baxter Medical